Reprogramming of profibrotic macrophages for treatment of bleomycin‐induced pulmonary fibrosis
Abstract Fibrotic diseases cause organ failure that lead to ~45% of all deaths in the United States. Activated macrophages stimulate fibrosis by secreting cytokines that induce fibroblasts to synthesize collagen and extracellular matrix proteins. Although suppression of macrophage‐derived cytokine p...
Saved in:
| Main Authors: | Fenghua Zhang, Ehab A Ayaub, Bingbing Wang, Estela Puchulu‐Campanella, Yen‐Hsing Li, Suraj U Hettiarachchi, Spencer D Lindeman, Qian Luo, Sasmita Rout, Madduri Srinivasarao, Abigail Cox, Konstantin Tsoyi, Cheryl Nickerson‐Nutter, Ivan O Rosas, Philip S Low |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2020-06-01
|
| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/emmm.202012034 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Pulmonary cytotoxicity induced by bleomycin and methotrexate
by: Zh, V, Sheykh, et al.
Published: (2016-03-01) -
CLINICAL SIGNIFICANCE OF Toll2, Toll4, CD14, AND HLA-DR EXPRESSION ON THE MONOCYTES IN PATIENTS WITH SEPSIS
by: V. A. Lazanovich, et al.
Published: (2015-06-01) -
Toll‐like receptors in mammalian sperm
by: Takashi Umehara, et al.
Published: (2025-01-01) -
Chemical pleurodesis using bleomycin in treatment of patients with transsudative pleural effusion in hepatic failure
by: A. L. Akopov, et al.
Published: (2017-06-01) -
Pirfenidone combined with UC-MSCs reversed bleomycin-induced pulmonary fibrosis
by: Jingran Xu, et al.
Published: (2025-08-01)