Changes in Methylation Patterns of Tumor Suppressor Genes during Extended Human Embryonic Stem Cell Cultures

Changes in Methylation Patterns of Tumor Suppressor Genes during Extended Human Embryonic Stem Cell Cultures

While studies on embryonic stem cells have been actively conducted, little is known about the epigenetic mechanisms in human embryonic stem cells (hESCs) in extended culture systems. Here, we investigated whether CpG island (CGI) methylation patterns of 24 tumor suppressor genes could be maintained...

Full description

Saved in:

Bibliographic Details
Main Authors:	Kyung Min Kang, Jeoung Eun Lee, Ji Eun Park, Hyunjin Kim, Hee Yeon Jang, Minyeon Go, Dong Ryul Lee, Sung Han Shim
Format:	Article
Language:	English
Published:	Wiley 2021-01-01
Series:	Stem Cells International
Online Access:	http://dx.doi.org/10.1155/2021/5575185
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

First Indonesian Nasopharyngeal Cancer Whole Epigenome Sequencing Identify Tumour Suppressor CpG Methylation
by: Handoko, et al.
Published: (2025-01-01)

MOUSE AND HUMAN EMBRYONIC STEM CELLS
by: A. G. Menzorov
Published: (2014-12-01)

Factors Requiring Adjustment in the Interpretation of Serum Carcinoembryonic Antigen: A Cross-Sectional Study of 18,131 Healthy Nonsmokers
by: Hae Yeon Kang, et al.
Published: (2017-01-01)

Exacerbation of polyethylene microplastics in animal models of DSS-induced colitis through damage to intestinal epithelial cell conjunctions
by: Minkyoung Sung, et al.
Published: (2025-01-01)

Predicted indirectly recognizable HLA epitopes scores and clinical outcomes after haploidentical stem cell transplantation in pediatric patients with relapsed neuroblastoma
by: Eun Seop Seo, et al.
Published: (2025-01-01)

Corrigendum: Predicted indirectly recognizable HLA epitopes scores and clinical outcomes after haploidentical stem cell transplantation in pediatric patients with relapsed neuroblastoma
by: Eun Seop Seo, et al.
Published: (2025-02-01)

Novel role of microphthalmia-associated transcription factor in modulating the differentiation and immunosuppressive functions of myeloid-derived suppressor cells
by: Yoon Kyung Jeon, et al.
Published: (2023-01-01)

Electroporation of mouse embryonic stem cells with Neon device
by: I. P. Savchenkova, et al.
Published: (2022-09-01)

Mechanisms Regulating Stemness and Differentiation in Embryonal Carcinoma Cells
by: Gregory M. Kelly, et al.
Published: (2017-01-01)

Alternative Splicing in Self-Renewal of Embryonic Stem Cells
by: Clara Y. Cheong, et al.
Published: (2011-01-01)

Changes in the Expression of Mitochondrial Morphology-Related Genes during the Differentiation of Murine Embryonic Stem Cells
by: Jeong Eon Lee, et al.
Published: (2020-01-01)

Stemness-Attenuating miR-503-3p as a Paracrine Factor to Regulate Growth of Cancer Stem Cells
by: Minkoo Seo, et al.
Published: (2018-01-01)

A Case Report on Ductal Carcinoma in situ Arising from Axillary Accessory Breast Tissue
by: Kyung Eun Lee, et al.
Published: (2025-01-01)

Ethical Implications in the Use of Embryonic and Adult Neural Stem Cells
by: Rodrigo Ramos-Zúñiga, et al.
Published: (2012-01-01)

A Sweet Potion to Put Embryonic Stem Cells to Sleep
by: Kaushik D. Deb
Published: (2009-01-01)

Absence of Rybp Compromises Neural Differentiation of Embryonic Stem Cells
by: Gergo Kovacs, et al.
Published: (2016-01-01)

A Review of Three Different Studies on Hidden Markov Models for Epigenetic Problems: A Computational Perspective
by: Kyung-Eun Lee, et al.
Published: (2014-12-01)

Effect of BMP-2 Delivery Mode on Osteogenic Differentiation of Stem Cells
by: Taekhee Jung, et al.
Published: (2017-01-01)

The histopathological and functional consequences of microplastic exposure
by: Yujeong Lee, et al.
Published: (2025-01-01)

Holistic approach to adaptive reuse research focused on the design strategy and its extended categories: lessons from a critical review
by: Yoon-Jeong Shin, et al.
Published: (2025-02-01)

Single-Cell Landscape and a Macrophage Subset Enhancing Brown Adipocyte Function in Diabetes ( 2024;48:885-900)
by: Yea Eun Kang, et al.
Published: (2025-01-01)

Damage Identification by the Data Expansion and Substructuring Methods
by: Eun-Taik Lee, et al.
Published: (2018-01-01)

Differentiation of Human Embryonic Stem Cells into Neuron, Cholinergic, and Glial Cells
by: Kimia Hosseini, et al.
Published: (2020-01-01)

Enigma of Retrotransposon Biology in Mammalian Early Embryos and Embryonic Stem Cells
by: Ying Yin, et al.
Published: (2018-01-01)

Adherence to customized vestibular rehabilitation therapy: influencing factors and clinical implications in vestibulopathy
by: Yeon Hee Im, et al.
Published: (2025-02-01)

Epigenetic modulation of social cognition: exploring the impact of methylation in brain-derived neurotrophic factor and oxytocin receptor genes across sex
by: Hye Yoon Park, et al.
Published: (2025-01-01)

Effect of Human Mesenchymal Stem Cells on Xenogeneic T and B Cells Isolated from Lupus-Prone MRL.Faslpr Mice
by: Hong Kyung Lee, et al.
Published: (2020-01-01)

Undifferentiated Embryonal Sarcoma of the Liver Involving All Major Hepatic Veins Treated by Left Extended Trisectionectomy
by: Reinaldo Fernandes, et al.
Published: (2022-01-01)

Differentiation of Human Embryonic Stem Cells to Sympathetic Neurons: A Potential Model for Understanding Neuroblastoma Pathogenesis
by: Jane Carr-Wilkinson, et al.
Published: (2018-01-01)

Deep neuromuscular blockade during radiofrequency catheter ablation under general anesthesia reduces the prevalence of atrial fibrillation recurrence when compared to moderate neuromuscular blockade: A randomized controlled trial
by: Eun Jung Oh, et al.
Published: (2025-01-01)

Innate Immune Response of Human Embryonic Stem Cell-Derived Fibroblasts and Mesenchymal Stem Cells to Periodontopathogens
by: Gopu Sriram, et al.
Published: (2016-01-01)

An Alternative Method for Long-Term Culture of Chicken Embryonic Stem Cell In Vitro
by: Li Zhang, et al.
Published: (2018-01-01)

Stub1 maintains proteostasis of master transcription factors in embryonic stem cells
by: Md Mahfuz Al Mamun, et al.
Published: (2025-02-01)

Generation and characterization of the LINC01405 knockout human embryonic stem cell line
by: Yaping Xu, et al.
Published: (2025-02-01)

Strategies to Improve the Quality and Freshness of Human Bone Marrow-Derived Mesenchymal Stem Cells for Neurological Diseases
by: Da Yeon Lee, et al.
Published: (2021-01-01)

Genetic background and embryonic temperature affect DNA methylation and expression of myogenin and muscle development in Atlantic salmon (Salmo salar).
by: Erik Burgerhout, et al.
Published: (2017-01-01)

Developing JSequitur to Study the Hierarchical Structure of Biological Sequences in a Grammatical Inference Framework of String Compression Algorithms
by: Bulgan Galbadrakh, et al.
Published: (2012-12-01)

Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical Perspective
by: Heather Lent, et al.
Published: (2015-12-01)

Generation and Characterization of Erythroid Cells from Human Embryonic Stem Cells and Induced Pluripotent Stem Cells: An Overview
by: Kai-Hsin Chang, et al.
Published: (2011-01-01)

Efficient and Fast Differentiation of Human Neural Stem Cells from Human Embryonic Stem Cells for Cell Therapy
by: Xinxin Han, et al.
Published: (2017-01-01)