The Inhibition of Serum Amyloid A Protein Aggregation by a Five-Residue Peptidomimetic: Structural and Morphological Insights

The Inhibition of Serum Amyloid A Protein Aggregation by a Five-Residue Peptidomimetic: Structural and Morphological Insights

Serum amyloid A (SAA) is a small protein consisting of 104 residues and, under physiological conditions, exists mainly in hexameric form. It belongs to the positive acute-phase proteins, which means that its plasma concentration increases rapidly in response to injury, inflammation, and infection. T...

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Bibliographic Details
Main Authors: Julia Witkowska, Sandra Skibiszewska, Paweł Wityk, Marcel Pilarski, Elżbieta Jankowska
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Molecules
Subjects:
serum amyloid A
aggregation
inhibitor
Online Access:https://www.mdpi.com/1420-3049/29/21/5165
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