Blood based immune biomarkers associated with clinical frailty scale in older patients with melanoma receiving checkpoint inhibitor immunotherapy

Blood based immune biomarkers associated with clinical frailty scale in older patients with melanoma receiving checkpoint inhibitor immunotherapy

Abstract Introduction Immunotherapy with checkpoint inhibition (ICI) is increasingly prescribed to older patients with cancer. High age, especially in combination with frailty, has been associated to immune senescence, which is the age-related decline in immune function, thereby possibly hindering I...

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Main Authors:	Estelle Tran Van Hoi, Saskia J. Santegoets, Simon P. Mooijaart, Diana Van Heemst, Asli Özkan, Elizabeth M. E. Verdegaal, Marije Slingerland, Ellen Kapiteijn, Sjoerd H. van der Burg, Johanneke E. A. Portielje, Marij J. P. Welters, Nienke A. de Glas
Format:	Article
Language:	English
Published:	BMC 2024-11-01
Series:	Immunity & Ageing
Subjects:	Melanoma cancer Immunotherapy by checkpoint inhibition Frailty Immune biomarkers
Online Access:	https://doi.org/10.1186/s12979-024-00463-y
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