The performance of JAM3/PAX1 methylation in the diagnosis of high-grade squamous intraepithelial lesions for women with high-risk HPV infection

The performance of JAM3/PAX1 methylation in the diagnosis of high-grade squamous intraepithelial lesions for women with high-risk HPV infection

Abstract Objective To assess the clinical value of DNA methylation measurement in exfoliated cervical cells for distinguishing high-grade squamous intraepithelial lesions (HSIL) from other cervical abnormalities. Methods A total of 276 patients were enrolled, and general clinical information was col...

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Bibliographic Details
Main Authors: Dan Sun, Changfa Shu, Fei Zeng, Dabao Xu, Xingping Zhao
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Cancer
Subjects:
High-grade squamous intraepithelial lesions
DNA methylation
JAM3
PAX1
Hr-HPV
Online Access:https://doi.org/10.1186/s12885-024-13299-y
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