Using the PET/CT radiotracer [68Ga]Ga-DOTA-mDesmo to target V1b receptors and localize corticotropinoma in Cushing’s disease

Using the PET/CT radiotracer [68Ga]Ga-DOTA-mDesmo to target V1b receptors and localize corticotropinoma in Cushing’s disease

Abstract Background Cushing’s disease, the most common cause of Cushing’s syndrome, is driven by pituitary tumors (corticotropinoma) and characterized by the overexpression of CRH R1 and V1b receptors. Accurate detection of these tumors remains challenging. This study aims to develop and evaluate a...

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Bibliographic Details
Main Authors: Somit Pandey, Rama Walia, Gurvinder Kaur, Kumud Pandav, Imran Rather, Nivedita Rana, Sushant Sahoo, Bhagwant Rai Mittal, Jaya Shukla
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-025-01033-z
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