Histopathological Perspective of Linear and Whorled Nevoid Hypermelanosis in Adulthood: A Rare Case Report
A rare pigmentation disorder called linear and whorled nevoid hypermelanosis (LWNH) is characterized by macular hyperpigmentation that follows the Blaschko lines. The cheeks, palms, soles, and mucosae are typically spared from lesions and are typically limited to the trunk, neck, and extremities. Al...
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| Language: | English |
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Wolters Kluwer Medknow Publications
2024-11-01
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| Series: | Medical Journal of Dr. D.Y. Patil Vidyapeeth |
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| Online Access: | https://journals.lww.com/10.4103/mjdrdypu.mjdrdypu_116_24 |
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| author | Banyameen Iqbal Srishti Malla Tushar Kambale Nayonikha Deokar |
| author_facet | Banyameen Iqbal Srishti Malla Tushar Kambale Nayonikha Deokar |
| author_sort | Banyameen Iqbal |
| collection | DOAJ |
| description | A rare pigmentation disorder called linear and whorled nevoid hypermelanosis (LWNH) is characterized by macular hyperpigmentation that follows the Blaschko lines. The cheeks, palms, soles, and mucosae are typically spared from lesions and are typically limited to the trunk, neck, and extremities. Although it is usually benign, there have been reports of associations with many congenital abnormalities. Herein, we present a rare case of LWNH involving the lateral surface of the abdomen in a 22-year-old male patient. A punch biopsy from the skin was received, and based on the histomorphological features, a diagnosis of LWNH was given. Hence, histopathology is the gold standard and confirmatory tool for definite diagnosis, along with other dermatological and genetic investigations in this case. |
| format | Article |
| id | doaj-art-6b377a59f89f4b5d83877e3a1386797f |
| institution | Kabale University |
| issn | 2589-8302 2589-8310 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Medical Journal of Dr. D.Y. Patil Vidyapeeth |
| spelling | doaj-art-6b377a59f89f4b5d83877e3a1386797f2024-12-12T07:34:25ZengWolters Kluwer Medknow PublicationsMedical Journal of Dr. D.Y. Patil Vidyapeeth2589-83022589-83102024-11-0117Suppl 2S371S37310.4103/mjdrdypu.mjdrdypu_116_24Histopathological Perspective of Linear and Whorled Nevoid Hypermelanosis in Adulthood: A Rare Case ReportBanyameen IqbalSrishti MallaTushar KambaleNayonikha DeokarA rare pigmentation disorder called linear and whorled nevoid hypermelanosis (LWNH) is characterized by macular hyperpigmentation that follows the Blaschko lines. The cheeks, palms, soles, and mucosae are typically spared from lesions and are typically limited to the trunk, neck, and extremities. Although it is usually benign, there have been reports of associations with many congenital abnormalities. Herein, we present a rare case of LWNH involving the lateral surface of the abdomen in a 22-year-old male patient. A punch biopsy from the skin was received, and based on the histomorphological features, a diagnosis of LWNH was given. Hence, histopathology is the gold standard and confirmatory tool for definite diagnosis, along with other dermatological and genetic investigations in this case.https://journals.lww.com/10.4103/mjdrdypu.mjdrdypu_116_24blaschko lineskaryotypinglinear and whorled nevoid hypermelanosis |
| spellingShingle | Banyameen Iqbal Srishti Malla Tushar Kambale Nayonikha Deokar Histopathological Perspective of Linear and Whorled Nevoid Hypermelanosis in Adulthood: A Rare Case Report Medical Journal of Dr. D.Y. Patil Vidyapeeth blaschko lines karyotyping linear and whorled nevoid hypermelanosis |
| title | Histopathological Perspective of Linear and Whorled Nevoid Hypermelanosis in Adulthood: A Rare Case Report |
| title_full | Histopathological Perspective of Linear and Whorled Nevoid Hypermelanosis in Adulthood: A Rare Case Report |
| title_fullStr | Histopathological Perspective of Linear and Whorled Nevoid Hypermelanosis in Adulthood: A Rare Case Report |
| title_full_unstemmed | Histopathological Perspective of Linear and Whorled Nevoid Hypermelanosis in Adulthood: A Rare Case Report |
| title_short | Histopathological Perspective of Linear and Whorled Nevoid Hypermelanosis in Adulthood: A Rare Case Report |
| title_sort | histopathological perspective of linear and whorled nevoid hypermelanosis in adulthood a rare case report |
| topic | blaschko lines karyotyping linear and whorled nevoid hypermelanosis |
| url | https://journals.lww.com/10.4103/mjdrdypu.mjdrdypu_116_24 |
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