RUNX1 promotes proliferation of cervical cancer through TGFB2-MAPK pathway

RUNX1 promotes proliferation of cervical cancer through TGFB2-MAPK pathway

Abstract As cervical cancer (CC) caused more than 300,000 deaths in the world, it is urgent to identify therapeutic targets to improve survival. Though RUNX1 is overexpressed in CC, its specific role and underlying molecular mechanisms remain incompletely understood. Here we presented that RUNX1 was...

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Bibliographic Details
Main Authors: Yongqin Jia, Neng Yang, Shuai Tang, Li Deng, Yanzhou Wang, Xiongwei Cai
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Cervical cancer
RUNX1
Proliferation
MAPK pathway
TGFB2
Immune microenvironment
Online Access:https://doi.org/10.1038/s41598-024-84254-x
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