Advanced applications of smart electrospun nanofibers in cancer therapy: With insight into material capabilities and electrospinning parameters
Cancer remains a major global health challenge, and despite available treatments, its prognosis remains poor. Recently, researchers have turned their attention to intelligent nanofibers for cancer drug delivery. These nanofibers exhibit remarkable capabilities in targeted and controlled drug release...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-12-01
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| Series: | International Journal of Pharmaceutics: X |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590156724000379 |
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| author | Vahid Tayebi-Khorrami Pouria Rahmanian-Devin Mohammad Reza Fadaei Jebraeel Movaffagh Vahid Reza Askari |
| author_facet | Vahid Tayebi-Khorrami Pouria Rahmanian-Devin Mohammad Reza Fadaei Jebraeel Movaffagh Vahid Reza Askari |
| author_sort | Vahid Tayebi-Khorrami |
| collection | DOAJ |
| description | Cancer remains a major global health challenge, and despite available treatments, its prognosis remains poor. Recently, researchers have turned their attention to intelligent nanofibers for cancer drug delivery. These nanofibers exhibit remarkable capabilities in targeted and controlled drug release. Their inherent characteristics, such as a high surface area-to-volume ratio, make them attractive candidates for drug delivery applications. Smart nanofibers can release drugs in response to specific stimuli, including pH, temperature, magnetic fields, and light. This unique feature not only reduces side effects but also enhances the overall efficiency of drug delivery systems. Electrospinning, a widely used method, allows the precision fabrication of smart nanofibers. Its advantages include high efficiency, user-friendliness, and the ability to control various manufacturing parameters. In this review, we explore the latest developments in producing smart electrospun nanofibers for cancer treatment. Additionally, we discuss the materials used in manufacturing these nanofibers and the critical parameters involved in the electrospinning process. |
| format | Article |
| id | doaj-art-6af94af9e3054c5e9a00cf1d9c4693f4 |
| institution | Kabale University |
| issn | 2590-1567 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Pharmaceutics: X |
| spelling | doaj-art-6af94af9e3054c5e9a00cf1d9c4693f42024-12-17T05:00:33ZengElsevierInternational Journal of Pharmaceutics: X2590-15672024-12-018100265Advanced applications of smart electrospun nanofibers in cancer therapy: With insight into material capabilities and electrospinning parametersVahid Tayebi-Khorrami0Pouria Rahmanian-Devin1Mohammad Reza Fadaei2Jebraeel Movaffagh3Vahid Reza Askari4Department of Pharmaceutics, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Pharmaceutics, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Pharmaceutics, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Pharmaceutics, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, IranPharmacological Research Center of Medicinal Plants, Mashhad University of Medical Sciences, Mashhad, Iran; Corresponding author at: Pharmacological Research Center of Medicinal Plants, Mashhad University of Medical Sciences, Azadi Sq, Vakil Abad Highway, Mashhad 9177948564, Iran.Cancer remains a major global health challenge, and despite available treatments, its prognosis remains poor. Recently, researchers have turned their attention to intelligent nanofibers for cancer drug delivery. These nanofibers exhibit remarkable capabilities in targeted and controlled drug release. Their inherent characteristics, such as a high surface area-to-volume ratio, make them attractive candidates for drug delivery applications. Smart nanofibers can release drugs in response to specific stimuli, including pH, temperature, magnetic fields, and light. This unique feature not only reduces side effects but also enhances the overall efficiency of drug delivery systems. Electrospinning, a widely used method, allows the precision fabrication of smart nanofibers. Its advantages include high efficiency, user-friendliness, and the ability to control various manufacturing parameters. In this review, we explore the latest developments in producing smart electrospun nanofibers for cancer treatment. Additionally, we discuss the materials used in manufacturing these nanofibers and the critical parameters involved in the electrospinning process.http://www.sciencedirect.com/science/article/pii/S2590156724000379SmartNanofibersElectrospinningDrug deliveryCancer |
| spellingShingle | Vahid Tayebi-Khorrami Pouria Rahmanian-Devin Mohammad Reza Fadaei Jebraeel Movaffagh Vahid Reza Askari Advanced applications of smart electrospun nanofibers in cancer therapy: With insight into material capabilities and electrospinning parameters International Journal of Pharmaceutics: X Smart Nanofibers Electrospinning Drug delivery Cancer |
| title | Advanced applications of smart electrospun nanofibers in cancer therapy: With insight into material capabilities and electrospinning parameters |
| title_full | Advanced applications of smart electrospun nanofibers in cancer therapy: With insight into material capabilities and electrospinning parameters |
| title_fullStr | Advanced applications of smart electrospun nanofibers in cancer therapy: With insight into material capabilities and electrospinning parameters |
| title_full_unstemmed | Advanced applications of smart electrospun nanofibers in cancer therapy: With insight into material capabilities and electrospinning parameters |
| title_short | Advanced applications of smart electrospun nanofibers in cancer therapy: With insight into material capabilities and electrospinning parameters |
| title_sort | advanced applications of smart electrospun nanofibers in cancer therapy with insight into material capabilities and electrospinning parameters |
| topic | Smart Nanofibers Electrospinning Drug delivery Cancer |
| url | http://www.sciencedirect.com/science/article/pii/S2590156724000379 |
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