Palbociclib as an Antitumor Drug: A License to Kill

Neoplastic cells are characterized by uncontrolled cell divisions caused by cell cycle dysregulation. Key regulatory proteins governing the transition from the G1 to the S phase are the CDK4 and CDK6 kinases, which are controlled by D-type cyclins. The CDK4/6 kinases enable the use of these proteins...

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Bibliographic Details
Main Authors: Agnieszka Łupicka-Słowik, Federica Cossu, Marcin Sieńczyk
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Molecules
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Online Access:https://www.mdpi.com/1420-3049/29/22/5334
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