Analysis of study Global Burden of Disease in 2021: global, regional, and national burden of nutritional deficiency from 1990 to 2021

BackgroundNutrient deficiency disorders (NDs) harm growth, causing economic losses. Addressing NDs is a global priority, yet recent data is limited. This study examines latest NDs data across 204 countries and 21 regions from 1990 to 2021.MethodsData from the 2021 Global Burden of Disease (GBD) stud...

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Main Authors: Jing Chen, Zedong Li, Hong Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Nutrition
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Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2024.1540485/full
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author Jing Chen
Zedong Li
Hong Liu
author_facet Jing Chen
Zedong Li
Hong Liu
author_sort Jing Chen
collection DOAJ
description BackgroundNutrient deficiency disorders (NDs) harm growth, causing economic losses. Addressing NDs is a global priority, yet recent data is limited. This study examines latest NDs data across 204 countries and 21 regions from 1990 to 2021.MethodsData from the 2021 Global Burden of Disease (GBD) study were used to analyze NDs-related incidence, prevalence, deaths, and disability-adjusted life years (DALYs) at global, national, and regional levels. Joinpoint regression analysis was applied to evaluate temporal trends, with Estimated Annual Percentage Change (EAPC) assessing long-term patterns.ResultsIn 2021, the global burden of NDs remained substantial, with a total of 1,845,246,558 cases with an ASPR of 23,858.99 cases per 100,000 individuals (95% UI: 23,445.77–24,320.82). The ASIR was 7,725.1 per 100,000 people (95% UI: 7,404.01–8,109.01), while the ASMR was 3.03 per 100,000 persons (95% UI: 2.69–3.4). Additionally, age-standardized DALYs rate was 657.62 per 100,000 individuals (95% UI: 489.93–869.58). Regionally, areas with low SDI exhibited the greatest ASPR, ASIR, ASDR, and age-standardized DALYs rates, whereas high SDI regions had the lowest rates.ConclusionsAlthough global NDs burden has declined from 1990 to 2021, regional and demographic disparities remain. Enhanced healthcare access in high-risk SDI regions is essential to further mitigate NDs's global impact.
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spelling doaj-art-6abc1a05e0304734a8dd0d39d383ecdc2025-01-15T05:10:08ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2025-01-011110.3389/fnut.2024.15404851540485Analysis of study Global Burden of Disease in 2021: global, regional, and national burden of nutritional deficiency from 1990 to 2021Jing Chen0Zedong Li1Hong Liu2Department of Surgery, Institute of Integrated Traditional Chinese and Western Medicine, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Gastrointestinal Surgery, Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Surgery, Integrated Traditional and Western Medicine, West China Hospital, Sichuan University, Chengdu, ChinaBackgroundNutrient deficiency disorders (NDs) harm growth, causing economic losses. Addressing NDs is a global priority, yet recent data is limited. This study examines latest NDs data across 204 countries and 21 regions from 1990 to 2021.MethodsData from the 2021 Global Burden of Disease (GBD) study were used to analyze NDs-related incidence, prevalence, deaths, and disability-adjusted life years (DALYs) at global, national, and regional levels. Joinpoint regression analysis was applied to evaluate temporal trends, with Estimated Annual Percentage Change (EAPC) assessing long-term patterns.ResultsIn 2021, the global burden of NDs remained substantial, with a total of 1,845,246,558 cases with an ASPR of 23,858.99 cases per 100,000 individuals (95% UI: 23,445.77–24,320.82). The ASIR was 7,725.1 per 100,000 people (95% UI: 7,404.01–8,109.01), while the ASMR was 3.03 per 100,000 persons (95% UI: 2.69–3.4). Additionally, age-standardized DALYs rate was 657.62 per 100,000 individuals (95% UI: 489.93–869.58). Regionally, areas with low SDI exhibited the greatest ASPR, ASIR, ASDR, and age-standardized DALYs rates, whereas high SDI regions had the lowest rates.ConclusionsAlthough global NDs burden has declined from 1990 to 2021, regional and demographic disparities remain. Enhanced healthcare access in high-risk SDI regions is essential to further mitigate NDs's global impact.https://www.frontiersin.org/articles/10.3389/fnut.2024.1540485/fullnutritional deficienciesGBDDALYstrend projectionsSocial Development Index
spellingShingle Jing Chen
Zedong Li
Hong Liu
Analysis of study Global Burden of Disease in 2021: global, regional, and national burden of nutritional deficiency from 1990 to 2021
Frontiers in Nutrition
nutritional deficiencies
GBD
DALYs
trend projections
Social Development Index
title Analysis of study Global Burden of Disease in 2021: global, regional, and national burden of nutritional deficiency from 1990 to 2021
title_full Analysis of study Global Burden of Disease in 2021: global, regional, and national burden of nutritional deficiency from 1990 to 2021
title_fullStr Analysis of study Global Burden of Disease in 2021: global, regional, and national burden of nutritional deficiency from 1990 to 2021
title_full_unstemmed Analysis of study Global Burden of Disease in 2021: global, regional, and national burden of nutritional deficiency from 1990 to 2021
title_short Analysis of study Global Burden of Disease in 2021: global, regional, and national burden of nutritional deficiency from 1990 to 2021
title_sort analysis of study global burden of disease in 2021 global regional and national burden of nutritional deficiency from 1990 to 2021
topic nutritional deficiencies
GBD
DALYs
trend projections
Social Development Index
url https://www.frontiersin.org/articles/10.3389/fnut.2024.1540485/full
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AT zedongli analysisofstudyglobalburdenofdiseasein2021globalregionalandnationalburdenofnutritionaldeficiencyfrom1990to2021
AT hongliu analysisofstudyglobalburdenofdiseasein2021globalregionalandnationalburdenofnutritionaldeficiencyfrom1990to2021