EEPD1 attenuates radiation-induced cardiac hypertrophy and apoptosis by degrading FOXO3A in cardiomyocytes

EEPD1 attenuates radiation-induced cardiac hypertrophy and apoptosis by degrading FOXO3A in cardiomyocytes

Radiation-induced heart disease (RIHD) is a severe delayed complication of thoracic irradiation (IR). Endonuclease/exonuclease/phosphatase family domain-containing 1 (EEPD1) plays an important role in DNA damage repair, but its role in RIHD...

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Bibliographic Details
Main Authors: Yu Kaiwen, Su Xi, Zhou Tongfang, Cai Xuwei, Zhang Min
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2024-08-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
<italic>EEPD1</italic>
radiation-induced heart disease
cardiac hypertrophy
apoptosis
<italic>FOXO3A</italic>
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2024130
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