Understanding the Epidemiology of Monkeypox Virus to Prevent Future Outbreaks
Monkeypox (Mpox) is an infectious disease caused by the Mpox virus belonging to the Orthopoxvirus genus in the Poxviridae family and has been declared by the WHO as a global health emergency owing to its rapid spread during 2022 and 2023. All patients diagnosed with Mpox who were confirmed by PCR be...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-12-01
|
| Series: | Microorganisms |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-2607/12/12/2576 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1846103506306465792 |
|---|---|
| author | Jimmy Steven Velásquez Fabiola Beatriz Herrera-Echeverría Héctor Salvador Porres-Paredes Carmen Rodríguez-Cerdeira |
| author_facet | Jimmy Steven Velásquez Fabiola Beatriz Herrera-Echeverría Héctor Salvador Porres-Paredes Carmen Rodríguez-Cerdeira |
| author_sort | Jimmy Steven Velásquez |
| collection | DOAJ |
| description | Monkeypox (Mpox) is an infectious disease caused by the Mpox virus belonging to the Orthopoxvirus genus in the Poxviridae family and has been declared by the WHO as a global health emergency owing to its rapid spread during 2022 and 2023. All patients diagnosed with Mpox who were confirmed by PCR between July 2022 and April 2023 were included in this study. In total, 405 patients in whom clade 2 was identified were included. Notably, 99% of included patients were men, with 82% of them aged 20–39 years. Furthermore, 71% were men who had sex with men, and 34% were HIV carriers. Regarding the morphology of the lesions, approximately 63% presented with papulonecrotic rash, which sometimes alternated with pustules depending on the stage they were in. All patients presented with systemic symptoms. Five patients required hospital admission, one of whom died, and presented with HIV and severe immunosuppression. Clinical findings suggest that contact during sexual intercourse is the most likely transmission mechanism and genital involvement is the most frequent clinical form. HIV was the primary comorbidity. Genital lesions were common, especially in vulnerable populations such as those who engage in high-risk sexual behaviors. |
| format | Article |
| id | doaj-art-6a2649e3f9e548e98f9529ab63ae55b9 |
| institution | Kabale University |
| issn | 2076-2607 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj-art-6a2649e3f9e548e98f9529ab63ae55b92024-12-27T14:41:36ZengMDPI AGMicroorganisms2076-26072024-12-011212257610.3390/microorganisms12122576Understanding the Epidemiology of Monkeypox Virus to Prevent Future OutbreaksJimmy Steven Velásquez0Fabiola Beatriz Herrera-Echeverría1Héctor Salvador Porres-Paredes2Carmen Rodríguez-Cerdeira3Dermatology Department, Hospital Regional de Occidente San Juan de Dios, Quetzaltenango 09001, GuatemalaDermatology Department, Hospital General San Juan de Dios, Guatemala 01001, GuatemalaDermatology Department, Hospital Regional de Occidente San Juan de Dios, Quetzaltenango 09001, GuatemalaFundación Vithas, Grupo Hospitalario Vithas, 28043 Madrid, SpainMonkeypox (Mpox) is an infectious disease caused by the Mpox virus belonging to the Orthopoxvirus genus in the Poxviridae family and has been declared by the WHO as a global health emergency owing to its rapid spread during 2022 and 2023. All patients diagnosed with Mpox who were confirmed by PCR between July 2022 and April 2023 were included in this study. In total, 405 patients in whom clade 2 was identified were included. Notably, 99% of included patients were men, with 82% of them aged 20–39 years. Furthermore, 71% were men who had sex with men, and 34% were HIV carriers. Regarding the morphology of the lesions, approximately 63% presented with papulonecrotic rash, which sometimes alternated with pustules depending on the stage they were in. All patients presented with systemic symptoms. Five patients required hospital admission, one of whom died, and presented with HIV and severe immunosuppression. Clinical findings suggest that contact during sexual intercourse is the most likely transmission mechanism and genital involvement is the most frequent clinical form. HIV was the primary comorbidity. Genital lesions were common, especially in vulnerable populations such as those who engage in high-risk sexual behaviors.https://www.mdpi.com/2076-2607/12/12/2576monkeypoxMSMHIVgenital ulcers |
| spellingShingle | Jimmy Steven Velásquez Fabiola Beatriz Herrera-Echeverría Héctor Salvador Porres-Paredes Carmen Rodríguez-Cerdeira Understanding the Epidemiology of Monkeypox Virus to Prevent Future Outbreaks Microorganisms monkeypox MSM HIV genital ulcers |
| title | Understanding the Epidemiology of Monkeypox Virus to Prevent Future Outbreaks |
| title_full | Understanding the Epidemiology of Monkeypox Virus to Prevent Future Outbreaks |
| title_fullStr | Understanding the Epidemiology of Monkeypox Virus to Prevent Future Outbreaks |
| title_full_unstemmed | Understanding the Epidemiology of Monkeypox Virus to Prevent Future Outbreaks |
| title_short | Understanding the Epidemiology of Monkeypox Virus to Prevent Future Outbreaks |
| title_sort | understanding the epidemiology of monkeypox virus to prevent future outbreaks |
| topic | monkeypox MSM HIV genital ulcers |
| url | https://www.mdpi.com/2076-2607/12/12/2576 |
| work_keys_str_mv | AT jimmystevenvelasquez understandingtheepidemiologyofmonkeypoxvirustopreventfutureoutbreaks AT fabiolabeatrizherreraecheverria understandingtheepidemiologyofmonkeypoxvirustopreventfutureoutbreaks AT hectorsalvadorporresparedes understandingtheepidemiologyofmonkeypoxvirustopreventfutureoutbreaks AT carmenrodriguezcerdeira understandingtheepidemiologyofmonkeypoxvirustopreventfutureoutbreaks |