Local Exosome Inhibition Potentiates Mild Photothermal Immunotherapy Against Breast Cancer

Local Exosome Inhibition Potentiates Mild Photothermal Immunotherapy Against Breast Cancer

Abstract Limited immune infiltration within the tumor microenvironment (TME) hampers the efficacy of immune checkpoint blockade (ICB) therapy. To enhance immune infiltration, mild photothermal therapy (PTT) is often combined with immunotherapy. However, the impact of mild PTT on the TME remains uncl...

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Main Authors: Qian Chen, Yanan Li, Jiameng Hu, Zhenyu Xu, Shengyi Wang, Naicong Cai, Mengjiao He, Yifang Xiao, Yuan Ding, Mengjuan Sun, Chunjiayu Li, Yiyang Cao, Zhongyuan Wang, Fang Zhou, Guangji Wang, Chen Wang, Jiasheng Tu, Haiyang Hu, Chunmeng Sun
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Advanced Science
Subjects:
combination immunotherapy
exosome inhibition
immune checkpoint blockade
mild photothermal therapy
multistage drug depot
Online Access:https://doi.org/10.1002/advs.202406328
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