Kinetics of the amino acid uptake tracer O-(2-[18F]fluoroethyl)-L-tyrosine (FET) in human brain

Kinetics of the amino acid uptake tracer O-(2-[18F]fluoroethyl)-L-tyrosine (FET) in human brain

Abstract Background The large neutral amino acid [18F]fluoroethoxy-L-tyrosine ([18F]FET) is a popular tracer for detection and staging of intracranial tumors by positron emission tomography (PET). While its high tumoral uptake reflects over-expression of the L-type amino acid transporter (LAT1), the...

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Bibliographic Details
Main Authors:	Korbinian Krieger, Thomas Pyka, Clemens Mingels, Hasan Sari, Albert Gjedde, Axel Rominger, Paul Cumming
Format:	Article
Language:	English
Published:	SpringerOpen 2025-07-01
Series:	EJNMMI Research
Subjects:	Positron emission tomography (PET) [18F]Fluoroethoxy-L-tyrosine (FET) Physiological Brain Large neutral amino acids L-type amino acid transporter
Online Access:	https://doi.org/10.1186/s13550-025-01279-7
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