Evoked bioelectrical activity of efferent fibers of the sciatic nerve of white rats in experimental menopause.
The aim of our work was analysis of the bioelectrical activity of efferent fibers of the sciatic nerve in experimental menopause condition. Experiments were performed on 25 female white rats, divided into experimental and control groups. Menopause was modeled by total ovariohysterectomy. In 120 days...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dnipro State Medical University
2016-03-01
|
| Series: | Medičnì Perspektivi |
| Subjects: | |
| Online Access: | http://journals.uran.ua/index.php/2307-0404/article/view/63440 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1846098192122249216 |
|---|---|
| author | A. G. Rodinsky S. S. Tkachenko L. V. Guz |
| author_facet | A. G. Rodinsky S. S. Tkachenko L. V. Guz |
| author_sort | A. G. Rodinsky |
| collection | DOAJ |
| description | The aim of our work was analysis of the bioelectrical activity of efferent fibers of the sciatic nerve in experimental menopause condition. Experiments were performed on 25 female white rats, divided into experimental and control groups. Menopause was modeled by total ovariohysterectomy. In 120 days after modeling we had recorded evoked action potentials of fibers of isolated ventral root L5 induced by stimulation of sciatic nerve with rectangular pulses. Threshold, chronaxia, latency, amplitude and duration of the action potential (AP) were analysed. Refractory phenomenon was investigated by applying paired stimuli at intervals of 2 to 20 ms. In the context of long-term hypoestrogenemy threshold of AP appearance was 55,32±7,69%, chronaxy – 115,09±2,67%, latent period – 112,62±1,74% as compared with the control animals (p<0.01). In conditions of paired stimuli applying the amplitude of response to the testing stimulus in animals with ovariohysterectomy at intervals 3 and 4 ms was 61,25±36,45% and 53,48±18,64% (p<0.05) respectively. |
| format | Article |
| id | doaj-art-68dfd322b28247b1b90f9ec32bfbe802 |
| institution | Kabale University |
| issn | 2307-0404 |
| language | English |
| publishDate | 2016-03-01 |
| publisher | Dnipro State Medical University |
| record_format | Article |
| series | Medičnì Perspektivi |
| spelling | doaj-art-68dfd322b28247b1b90f9ec32bfbe8022025-01-02T01:49:45ZengDnipro State Medical UniversityMedičnì Perspektivi2307-04042016-03-012114910.26641/2307-0404.2016.1.6344063440Evoked bioelectrical activity of efferent fibers of the sciatic nerve of white rats in experimental menopause.A. G. RodinskyS. S. TkachenkoL. V. GuzThe aim of our work was analysis of the bioelectrical activity of efferent fibers of the sciatic nerve in experimental menopause condition. Experiments were performed on 25 female white rats, divided into experimental and control groups. Menopause was modeled by total ovariohysterectomy. In 120 days after modeling we had recorded evoked action potentials of fibers of isolated ventral root L5 induced by stimulation of sciatic nerve with rectangular pulses. Threshold, chronaxia, latency, amplitude and duration of the action potential (AP) were analysed. Refractory phenomenon was investigated by applying paired stimuli at intervals of 2 to 20 ms. In the context of long-term hypoestrogenemy threshold of AP appearance was 55,32±7,69%, chronaxy – 115,09±2,67%, latent period – 112,62±1,74% as compared with the control animals (p<0.01). In conditions of paired stimuli applying the amplitude of response to the testing stimulus in animals with ovariohysterectomy at intervals 3 and 4 ms was 61,25±36,45% and 53,48±18,64% (p<0.05) respectively.http://journals.uran.ua/index.php/2307-0404/article/view/63440experimental menopauseelectrophysiological studiesventral roots |
| spellingShingle | A. G. Rodinsky S. S. Tkachenko L. V. Guz Evoked bioelectrical activity of efferent fibers of the sciatic nerve of white rats in experimental menopause. Medičnì Perspektivi experimental menopause electrophysiological studies ventral roots |
| title | Evoked bioelectrical activity of efferent fibers of the sciatic nerve of white rats in experimental menopause. |
| title_full | Evoked bioelectrical activity of efferent fibers of the sciatic nerve of white rats in experimental menopause. |
| title_fullStr | Evoked bioelectrical activity of efferent fibers of the sciatic nerve of white rats in experimental menopause. |
| title_full_unstemmed | Evoked bioelectrical activity of efferent fibers of the sciatic nerve of white rats in experimental menopause. |
| title_short | Evoked bioelectrical activity of efferent fibers of the sciatic nerve of white rats in experimental menopause. |
| title_sort | evoked bioelectrical activity of efferent fibers of the sciatic nerve of white rats in experimental menopause |
| topic | experimental menopause electrophysiological studies ventral roots |
| url | http://journals.uran.ua/index.php/2307-0404/article/view/63440 |
| work_keys_str_mv | AT agrodinsky evokedbioelectricalactivityofefferentfibersofthesciaticnerveofwhiteratsinexperimentalmenopause AT sstkachenko evokedbioelectricalactivityofefferentfibersofthesciaticnerveofwhiteratsinexperimentalmenopause AT lvguz evokedbioelectricalactivityofefferentfibersofthesciaticnerveofwhiteratsinexperimentalmenopause |