T cell induced expression of Coronin-1A facilitates blood-brain barrier transmigration of breast cancer cells
Abstract In previous work we discovered that T lymphocytes play a prominent role in the rise of brain metastases of ER-negative breast cancers. In the present study we explored how T lymphocytes promote breast cancer cell penetration through the blood brain barrier (BBB). An in vitro BBB model was e...
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| Main Authors: | Johan M. Kros, Lona Zeneyedpour, Rute M. S. M. Pedrosa, Zineb Belcaid, Willem A. Dik, Theo M. Luider, Dana A. M. Mustafa |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-12-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-024-83301-x |
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