Effect of onset of metabolic syndrome on allograft function in living donor’s kidney transplantation
ObjectiveTo observe the effect of onset of metabolic syndrome （MS） on allograft function after living donor’s kidney transplantation.MethodsFrom August 1，2012 to August 1，2014，clinical data were retrospectively analyzed for 120 recipients of living related renal transplantation. Statistical analysis...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Department of Journal of Clinical Nephrology
2022-01-01
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| Series: | Linchuang shenzangbing zazhi |
| Subjects: | |
| Online Access: | http://www.lcszb.com/thesisDetails#10.3969/j.issn.1671-2390.2022.01.006 |
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| Summary: | ObjectiveTo observe the effect of onset of metabolic syndrome （MS） on allograft function after living donor’s kidney transplantation.MethodsFrom August 1，2012 to August 1，2014，clinical data were retrospectively analyzed for 120 recipients of living related renal transplantation. Statistical analysis of serum creatine in MS and non-MS groups was conducted by SPSS 16.0 software at Month 3/6，Year 1/3/5 post-transplantation. And t-test was utilized for comparing two groups. Logistic regression was applied for risk factor analysis of MS and <italic>P</italic><0.05 was deemed as significant.ResultsNo significant inter-group difference existed in serum creatine at Month 3 post-transplantation. The mean value and standard deviation were （110.5±27.4） and （109.1±34.0） respectively （<italic>P</italic>>0.05）. At Month 6 post-transplantation，the mean value and standard deviation were （119.2±32.7） and （107.4±24.9） respectively （<italic>P</italic>>0.05）. Significant inter-group difference existed in serum creatine at Year 1 post-transplantation. The mean value and standard deviation were （133.6±39.6） and （106.2±19.2） respectively （<italic>P</italic><0.05）. At Year 3 post-transplantation，the mean value and standard deviation were （230.8±221.6） and （110.6±23.8） respectively （<italic>P</italic><0.01）. At Year 5 post-transplantation，the mean value and standard deviation were （266.2±103.1） and （113.6±26.4） respectively （<italic>P</italic><0.01）. Logistic regression revealed that the risk factors of MS were hyperuricemia，high triglyceride and low high density lipoprotein cholesterol.ConclusionMS is an important health problem in the recipients of kidney transplantation. It is imperative to develop targeted health education and intensify health management. |
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| ISSN: | 1671-2390 |