Heterogeneous survival upon disinfection underlies evolution of increased tolerance

Heterogeneous survival upon disinfection underlies evolution of increased tolerance

ABSTRACT Disinfection is important to limit the spread of infections, but failure of disinfection may foster the evolution of antimicrobial resistance in bacteria. Persisters are phenotypically tolerant subpopulations that survive toxic stress longer than susceptible cells, leading to failure in tre...

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Bibliographic Details
Main Authors: Niclas Nordholt, Lydia-Yasmin Sobisch, Annett Gödt, Dominique Lewerenz, Frank Schreiber
Format: Article
Language:English
Published: American Society for Microbiology 2024-12-01
Series:Microbiology Spectrum
Subjects:
disinfection
persisters
tolerance
evolution
survival
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03276-22
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