Transferability of new methods for health technology assessment in the field of diabetes between early and late adopters’ countries

This study aimed to investigate the transferability of novel artificial intelligence (AI) methods for prediction modelling of diabetes based on real-world data (RWD) between early and late adopters of emerging health technologies from the perspective of developers and health technology assessment (H...

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Main Authors: Konstantin Tachkov, Francisco Somolinos-Simón, Jose Tapia-Galisteo, Maria Elena Hernando, Gema García-Sáez, Maria Dimitrova, Maria Kamusheva, Zornitsa Mitkova, Zsuzsanna Petyko, Bertalan Nemeth, Zoltan Kalo, Tomas Tesar, Marian-Sorin Paveliu, Oresta Piniazhko, Iga Lipska, Adina Turcu-Stiolica, Alexandra Savova, Manoela Manova, Rok Hren, Petra Došenović Bonča, Saskia Knies, Michal Stanak, Tomáš Doležal, Dinko Vitezic, Guenka Petrova
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Biotechnology & Biotechnological Equipment
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Online Access:https://www.tandfonline.com/doi/10.1080/13102818.2024.2371354
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author Konstantin Tachkov
Francisco Somolinos-Simón
Jose Tapia-Galisteo
Maria Elena Hernando
Gema García-Sáez
Maria Dimitrova
Maria Kamusheva
Zornitsa Mitkova
Zsuzsanna Petyko
Bertalan Nemeth
Zoltan Kalo
Tomas Tesar
Marian-Sorin Paveliu
Oresta Piniazhko
Iga Lipska
Adina Turcu-Stiolica
Alexandra Savova
Manoela Manova
Rok Hren
Petra Došenović Bonča
Saskia Knies
Michal Stanak
Tomáš Doležal
Dinko Vitezic
Guenka Petrova
author_facet Konstantin Tachkov
Francisco Somolinos-Simón
Jose Tapia-Galisteo
Maria Elena Hernando
Gema García-Sáez
Maria Dimitrova
Maria Kamusheva
Zornitsa Mitkova
Zsuzsanna Petyko
Bertalan Nemeth
Zoltan Kalo
Tomas Tesar
Marian-Sorin Paveliu
Oresta Piniazhko
Iga Lipska
Adina Turcu-Stiolica
Alexandra Savova
Manoela Manova
Rok Hren
Petra Došenović Bonča
Saskia Knies
Michal Stanak
Tomáš Doležal
Dinko Vitezic
Guenka Petrova
author_sort Konstantin Tachkov
collection DOAJ
description This study aimed to investigate the transferability of novel artificial intelligence (AI) methods for prediction modelling of diabetes based on real-world data (RWD) between early and late adopters of emerging health technologies from the perspective of developers and health technology assessment (HTA) experts. A two-step approach was used. Developers of the new AI methods within HTx consortium completed a survey about the benefits, usability, barriers associated with implementing the new prediction models in routine HTA practices. Then, HTA experts from Central and Eastern European (CEE) countries participated in a focus group discussion. Developers generally expressed optimism regarding the transferability of the methods, while acknowledging potential disparities across CEE countries. Key benefits that were identified included enhanced understanding of diabetes, improved cost-effectiveness modelling, and refined patient stratification, all of which could contribute to clinical and reimbursement decisions across various jurisdictions. The focus group underscored the value of real-world data for diabetes prediction modelling, serving as a beneficial resource for both clinicians and HTA agencies. However, there was a recognized need to clarify the processes of integrating randomized clinical trial data with real-world data. For the other stakeholders, the advancement of the methodology will improve the diagnosis and therapy during the process of decision making. Experts from CEE countries recognized the potential of artificial intelligence-based methods employing real-world data for diabetes modelling. These methods are seen as instrumental in elucidating the heterogeneous nature of the disease, supporting clinician decision-making and holding promises for HTA purposes.
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spelling doaj-art-6868ed8c409341fb99bd9cda75a785752024-12-10T05:42:51ZengTaylor & Francis GroupBiotechnology & Biotechnological Equipment1310-28181314-35302024-12-0138110.1080/13102818.2024.2371354Transferability of new methods for health technology assessment in the field of diabetes between early and late adopters’ countriesKonstantin Tachkov0Francisco Somolinos-Simón1Jose Tapia-Galisteo2Maria Elena Hernando3Gema García-Sáez4Maria Dimitrova5Maria Kamusheva6Zornitsa Mitkova7Zsuzsanna Petyko8Bertalan Nemeth9Zoltan Kalo10Tomas Tesar11Marian-Sorin Paveliu12Oresta Piniazhko13Iga Lipska14Adina Turcu-Stiolica15Alexandra Savova16Manoela Manova17Rok Hren18Petra Došenović Bonča19Saskia Knies20Michal Stanak21Tomáš Doležal22Dinko Vitezic23Guenka Petrova24Department of Organization and Economics of Pharmacy, Faculty of Pharmacy, Medical University Sofia, Sofia, BulgariaCentre for Biomedical Technology (CTB), ETSI de Telecomunicación, Universidad Politécnica de Madrid, Madrid, SpainCentre for Biomedical Technology (CTB), ETSI de Telecomunicación, Universidad Politécnica de Madrid, Madrid, SpainCentre for Biomedical Technology (CTB), ETSI de Telecomunicación, Universidad Politécnica de Madrid, Madrid, SpainCentre for Biomedical Technology (CTB), ETSI de Telecomunicación, Universidad Politécnica de Madrid, Madrid, SpainDepartment of Organization and Economics of Pharmacy, Faculty of Pharmacy, Medical University Sofia, Sofia, BulgariaDepartment of Organization and Economics of Pharmacy, Faculty of Pharmacy, Medical University Sofia, Sofia, BulgariaDepartment of Organization and Economics of Pharmacy, Faculty of Pharmacy, Medical University Sofia, Sofia, BulgariaSYREON Research Institute, Budapest, HungarySYREON Research Institute, Budapest, HungarySYREON Research Institute, Budapest, HungaryDepartment of Organisation and Management in Pharmacy, Faculty of Pharmacy, Comenius University in Bratislava, Bratislava, SlovakiaFarmacologie Clinica/Farmacoeconomie, Titu Maiorescu University, Bucharest, RomaniaHTA Department of State Expert Centre of Ministry of Health, UkraineHealth Policy Institute, Warsaw, PolandFaculty of Pharmacy, University of Medicine and Pharmacy of Craiova, Craiova, RomaniaDepartment of Organization and Economics of Pharmacy, Faculty of Pharmacy, Medical University Sofia, Sofia, BulgariaDepartment of Organization and Economics of Pharmacy, Faculty of Pharmacy, Medical University Sofia, Sofia, BulgariaSYREON Research Institute, Budapest, HungarySchool of Economics and Business, University of Ljubljana, Ljubljana, SloveniaNational Institute for Value and Technologies in Healthcare, SlovakiaNational Institute for Value and Technologies in Healthcare, Bratislava, SlovakiaInstitute of Health Economics and Technology Assessment, Praga, CzechiaUniversity of Rijeka Medical School and University Hospital Centre, Rijeka, Rijeka, CroatiaDepartment of Organization and Economics of Pharmacy, Faculty of Pharmacy, Medical University Sofia, Sofia, BulgariaThis study aimed to investigate the transferability of novel artificial intelligence (AI) methods for prediction modelling of diabetes based on real-world data (RWD) between early and late adopters of emerging health technologies from the perspective of developers and health technology assessment (HTA) experts. A two-step approach was used. Developers of the new AI methods within HTx consortium completed a survey about the benefits, usability, barriers associated with implementing the new prediction models in routine HTA practices. Then, HTA experts from Central and Eastern European (CEE) countries participated in a focus group discussion. Developers generally expressed optimism regarding the transferability of the methods, while acknowledging potential disparities across CEE countries. Key benefits that were identified included enhanced understanding of diabetes, improved cost-effectiveness modelling, and refined patient stratification, all of which could contribute to clinical and reimbursement decisions across various jurisdictions. The focus group underscored the value of real-world data for diabetes prediction modelling, serving as a beneficial resource for both clinicians and HTA agencies. However, there was a recognized need to clarify the processes of integrating randomized clinical trial data with real-world data. For the other stakeholders, the advancement of the methodology will improve the diagnosis and therapy during the process of decision making. Experts from CEE countries recognized the potential of artificial intelligence-based methods employing real-world data for diabetes modelling. These methods are seen as instrumental in elucidating the heterogeneous nature of the disease, supporting clinician decision-making and holding promises for HTA purposes.https://www.tandfonline.com/doi/10.1080/13102818.2024.2371354Transferabilityhealth technology assessmentCentral and Easter European Countriesdiabetesartificial intelligence
spellingShingle Konstantin Tachkov
Francisco Somolinos-Simón
Jose Tapia-Galisteo
Maria Elena Hernando
Gema García-Sáez
Maria Dimitrova
Maria Kamusheva
Zornitsa Mitkova
Zsuzsanna Petyko
Bertalan Nemeth
Zoltan Kalo
Tomas Tesar
Marian-Sorin Paveliu
Oresta Piniazhko
Iga Lipska
Adina Turcu-Stiolica
Alexandra Savova
Manoela Manova
Rok Hren
Petra Došenović Bonča
Saskia Knies
Michal Stanak
Tomáš Doležal
Dinko Vitezic
Guenka Petrova
Transferability of new methods for health technology assessment in the field of diabetes between early and late adopters’ countries
Biotechnology & Biotechnological Equipment
Transferability
health technology assessment
Central and Easter European Countries
diabetes
artificial intelligence
title Transferability of new methods for health technology assessment in the field of diabetes between early and late adopters’ countries
title_full Transferability of new methods for health technology assessment in the field of diabetes between early and late adopters’ countries
title_fullStr Transferability of new methods for health technology assessment in the field of diabetes between early and late adopters’ countries
title_full_unstemmed Transferability of new methods for health technology assessment in the field of diabetes between early and late adopters’ countries
title_short Transferability of new methods for health technology assessment in the field of diabetes between early and late adopters’ countries
title_sort transferability of new methods for health technology assessment in the field of diabetes between early and late adopters countries
topic Transferability
health technology assessment
Central and Easter European Countries
diabetes
artificial intelligence
url https://www.tandfonline.com/doi/10.1080/13102818.2024.2371354
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