THE HEMATOLOGICAL EFFECT OF SALMONELLA TYPHIMURIUM ENDOTOXIN IN RABBITS
End toxin is responsible for different changes in body systems. This study was conducted to study hematological changes by using 20 rabbits, were randomly divided into 4 equal groups, then gave intravenous endotoxin doses 5, 15 and 20 µg/Kg body weight for groups I, II and III respectively, while gr...
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College of Veterinary Medicine, University of Basrah, Iraq
2008-12-01
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| Series: | Basrah Journal of Veterinary Research |
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| Online Access: | https://bjvr.uobasrah.edu.iq/article_55499_4063b534e4b8151434816d3f29bc7f7e.pdf |
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| author | Khalil H.Z. Al-Joboury Mohammed A.Y.Al-Amery Faisal G.Habasha |
| author_facet | Khalil H.Z. Al-Joboury Mohammed A.Y.Al-Amery Faisal G.Habasha |
| author_sort | Khalil H.Z. Al-Joboury |
| collection | DOAJ |
| description | End toxin is responsible for different changes in body systems. This study was conducted to study hematological changes by using 20 rabbits, were randomly divided into 4 equal groups, then gave intravenous endotoxin doses 5, 15 and 20 µg/Kg body weight for groups I, II and III respectively, while group IV gave PBS as a control.
The hematological findings included marked leukopenia due to neutropenia followed by marked leukocytosis with left shift associated with lymphocytosis, monocytosis and basophilia. Total erythrocytes, packed cell volume and hemoglobin concentration were increased during first hour, while the following time showed gradual decrease to develop anemia, which manifested by macrocytic hypochromic, in relation to the increased mean corpuscular volume and decreased mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration. Also thrombocytopenia, while the total plasma protein and fibrinogen showed pronounced increased due to endotoxemia |
| format | Article |
| id | doaj-art-685cf8c7fc9b4adf9da3b805ba7ff4c5 |
| institution | OA Journals |
| issn | 1813-8497 2410-8456 |
| language | English |
| publishDate | 2008-12-01 |
| publisher | College of Veterinary Medicine, University of Basrah, Iraq |
| record_format | Article |
| series | Basrah Journal of Veterinary Research |
| spelling | doaj-art-685cf8c7fc9b4adf9da3b805ba7ff4c52025-08-20T02:31:29ZengCollege of Veterinary Medicine, University of Basrah, IraqBasrah Journal of Veterinary Research1813-84972410-84562008-12-0172214310.33762/bvetr.2008.5549955499THE HEMATOLOGICAL EFFECT OF SALMONELLA TYPHIMURIUM ENDOTOXIN IN RABBITSKhalil H.Z. Al-JobouryMohammed A.Y.Al-Amery Faisal G.HabashaEnd toxin is responsible for different changes in body systems. This study was conducted to study hematological changes by using 20 rabbits, were randomly divided into 4 equal groups, then gave intravenous endotoxin doses 5, 15 and 20 µg/Kg body weight for groups I, II and III respectively, while group IV gave PBS as a control. The hematological findings included marked leukopenia due to neutropenia followed by marked leukocytosis with left shift associated with lymphocytosis, monocytosis and basophilia. Total erythrocytes, packed cell volume and hemoglobin concentration were increased during first hour, while the following time showed gradual decrease to develop anemia, which manifested by macrocytic hypochromic, in relation to the increased mean corpuscular volume and decreased mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration. Also thrombocytopenia, while the total plasma protein and fibrinogen showed pronounced increased due to endotoxemiahttps://bjvr.uobasrah.edu.iq/article_55499_4063b534e4b8151434816d3f29bc7f7e.pdfendotoxineleukopeniarabbits |
| spellingShingle | Khalil H.Z. Al-Joboury Mohammed A.Y.Al-Amery Faisal G.Habasha THE HEMATOLOGICAL EFFECT OF SALMONELLA TYPHIMURIUM ENDOTOXIN IN RABBITS Basrah Journal of Veterinary Research endotoxine leukopenia rabbits |
| title | THE HEMATOLOGICAL EFFECT OF SALMONELLA TYPHIMURIUM ENDOTOXIN IN RABBITS |
| title_full | THE HEMATOLOGICAL EFFECT OF SALMONELLA TYPHIMURIUM ENDOTOXIN IN RABBITS |
| title_fullStr | THE HEMATOLOGICAL EFFECT OF SALMONELLA TYPHIMURIUM ENDOTOXIN IN RABBITS |
| title_full_unstemmed | THE HEMATOLOGICAL EFFECT OF SALMONELLA TYPHIMURIUM ENDOTOXIN IN RABBITS |
| title_short | THE HEMATOLOGICAL EFFECT OF SALMONELLA TYPHIMURIUM ENDOTOXIN IN RABBITS |
| title_sort | hematological effect of salmonella typhimurium endotoxin in rabbits |
| topic | endotoxine leukopenia rabbits |
| url | https://bjvr.uobasrah.edu.iq/article_55499_4063b534e4b8151434816d3f29bc7f7e.pdf |
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