Effect of Trigonella Foenum – Graceum in Diabetic Albino Wistar Rats and Their Antioxidant Properties
Introduction: The WHO says diabetes is an incurable disease resulting from inadequate amounts of insulin produced by the β-cells of the pancreas or insufficient insulin use by the body. Diabetes mellitus is the 16th top cause of death globally. It is a crucial and significant public health problem....
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | Journal of Pharmacy and Bioallied Sciences |
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| Online Access: | https://journals.lww.com/10.4103/jpbs.jpbs_872_24 |
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| author | Komal Vishwakarma Zunjarrao G. Badade Archana Dhok Arvind Kushwaha Ranjit Ambad |
| author_facet | Komal Vishwakarma Zunjarrao G. Badade Archana Dhok Arvind Kushwaha Ranjit Ambad |
| author_sort | Komal Vishwakarma |
| collection | DOAJ |
| description | Introduction:
The WHO says diabetes is an incurable disease resulting from inadequate amounts of insulin produced by the β-cells of the pancreas or insufficient insulin use by the body. Diabetes mellitus is the 16th top cause of death globally. It is a crucial and significant public health problem. It is broadly recognized that people with diabetes have a higher chance of developing several major complications, like hypertension, hyperlipidemia, and diabetic obesity. Numerous animal models have been created over time to investigate diabetes mellitus or evaluate medications that prevent it. To generate diabetes in these models, several animal species are subjected to pharmacological, surgical (pancreatectomy), and genetic alterations.
Aims and Objectives:
To study in male Albino Wistar rats the potential anti-oxidant and anti-diabetic effects of fenugreek seeds.
Materials and Methods:
Male Wistar rats were given streptozotocin to cause diabetes; the rats were subsequently treated with fenugreek seeds. SOD and catalase levels in the serum of Wistar rats were used to determine fenugreek seeds anti-oxidant qualities.
Conclusion:
Using diabetic Albino Wistar rats, the study revealed Trigonella foenum has anti-diabetic and anti-oxidant qualities. |
| format | Article |
| id | doaj-art-683f3164b711403b90e0bb26bdf6b4db |
| institution | Kabale University |
| issn | 0976-4879 0975-7406 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Pharmacy and Bioallied Sciences |
| spelling | doaj-art-683f3164b711403b90e0bb26bdf6b4db2025-01-13T09:48:44ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062024-12-0116Suppl 4S3392S339410.4103/jpbs.jpbs_872_24Effect of Trigonella Foenum – Graceum in Diabetic Albino Wistar Rats and Their Antioxidant PropertiesKomal VishwakarmaZunjarrao G. BadadeArchana DhokArvind KushwahaRanjit AmbadIntroduction: The WHO says diabetes is an incurable disease resulting from inadequate amounts of insulin produced by the β-cells of the pancreas or insufficient insulin use by the body. Diabetes mellitus is the 16th top cause of death globally. It is a crucial and significant public health problem. It is broadly recognized that people with diabetes have a higher chance of developing several major complications, like hypertension, hyperlipidemia, and diabetic obesity. Numerous animal models have been created over time to investigate diabetes mellitus or evaluate medications that prevent it. To generate diabetes in these models, several animal species are subjected to pharmacological, surgical (pancreatectomy), and genetic alterations. Aims and Objectives: To study in male Albino Wistar rats the potential anti-oxidant and anti-diabetic effects of fenugreek seeds. Materials and Methods: Male Wistar rats were given streptozotocin to cause diabetes; the rats were subsequently treated with fenugreek seeds. SOD and catalase levels in the serum of Wistar rats were used to determine fenugreek seeds anti-oxidant qualities. Conclusion: Using diabetic Albino Wistar rats, the study revealed Trigonella foenum has anti-diabetic and anti-oxidant qualities.https://journals.lww.com/10.4103/jpbs.jpbs_872_24diabetic albino wistar rats and antioxidantgraceumtrigonella foenum |
| spellingShingle | Komal Vishwakarma Zunjarrao G. Badade Archana Dhok Arvind Kushwaha Ranjit Ambad Effect of Trigonella Foenum – Graceum in Diabetic Albino Wistar Rats and Their Antioxidant Properties Journal of Pharmacy and Bioallied Sciences diabetic albino wistar rats and antioxidant graceum trigonella foenum |
| title | Effect of Trigonella Foenum – Graceum in Diabetic Albino Wistar Rats and Their Antioxidant Properties |
| title_full | Effect of Trigonella Foenum – Graceum in Diabetic Albino Wistar Rats and Their Antioxidant Properties |
| title_fullStr | Effect of Trigonella Foenum – Graceum in Diabetic Albino Wistar Rats and Their Antioxidant Properties |
| title_full_unstemmed | Effect of Trigonella Foenum – Graceum in Diabetic Albino Wistar Rats and Their Antioxidant Properties |
| title_short | Effect of Trigonella Foenum – Graceum in Diabetic Albino Wistar Rats and Their Antioxidant Properties |
| title_sort | effect of trigonella foenum graceum in diabetic albino wistar rats and their antioxidant properties |
| topic | diabetic albino wistar rats and antioxidant graceum trigonella foenum |
| url | https://journals.lww.com/10.4103/jpbs.jpbs_872_24 |
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