LEVERAGING ORGANOID TECHNOLOGIES TO CHARACTERIZE DYNAMIC TUMOR CELL STATES DRIVING TREATMENT RESISTANCE IN PANCREATIC CANCER

Pancreatic ductal adenocarcinoma (PDAC) is characterized by a pronounced inter- and intra-tumoral heterogeneity, which fuels chemoresistance and contributes to high mortality rates. Previously, we have developed a branched organoid system embedded in collagen matrices that robustly recapitulates th...

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Bibliographic Details
Format: Article
Language:English
Published: PAGEPress Publications 2025-08-01
Series:European Journal of Histochemistry
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Online Access:https://www.ejh.it/ejh/article/view/4289
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