Staphylococcus aureus biofilm-associated component PNAG stimulates the secretion of the immunomodulatory chemokine CXCL10 via Dectin-1 signaling

Abstract Staphylococcus aureus is a common human pathogen associated with many infections. The key factor contributing to the virulence of S. aureus is its ability to form difficult-to-treat and recalcitrant biofilms. One of the major staphylococcal biofilms matrix compounds is poly-N-acetylglucosam...

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Bibliographic Details
Main Authors: Reza Gheitasi, Daniel Weiss, Mario M. Müller, Karolin Sommer, Daniela Röll, Alexander Mosig, Mathias. W. Pletz, Oliwia Makarewicz
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08503-z
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