Prevalence of Plasmodium falciparum plasmepsin2/3 gene duplication in Africa and Asia: a systematic review and meta-analysis

Prevalence of Plasmodium falciparum plasmepsin2/3 gene duplication in Africa and Asia: a systematic review and meta-analysis

Abstract Background The Plasmodium falciparum delayed clearance phenotype due to the emergence of partial artemisinin resistance has been documented in Asia and Africa, where it is associated with treatment failure of artemisinin-based combination therapy (ACT). The amplification of the Plasmodium f...

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Main Authors: Karol J. Marwa, Manase Kilonzi, Rajabu Hussein Mnkugwe, Vito Baraka, Anthony Kapesa, Richard Mwaiswelo, Maria Zinga, Bruno P. Mmbando, John P. A. Lusingu, Erasmus Kamugisha
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Malaria Journal
Subjects:
Plasmodium falciparum
Plasmepsin2/3
Amplification
Duplication
Africa
Asia
Online Access:https://doi.org/10.1186/s12936-025-05423-5
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https://doi.org/10.1186/s12936-025-05423-5

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