Malignant myoepithelial tumor of the right fibula in a young female: A case report

Myoepithelial tumors are extremely rare tumors, with only about 30 cases reported in the literature to date. We present the case of a 27-year-old female diagnosed with malignant right fibula myoepithelial tumor/myoepithelial carcinoma, initially treated with systemic chemotherapy. During treatment,...

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Main Authors: Tasneem AbuShaikha, Saja Alzboun, Ameer Alhosheyeh, Imad Aljaafreh, Ahmad Alhalabia, Haytham Shaban, Ahmed Barbarawi, Yazan Haddar, Farah Awad, Elias Edward Lahham
Format: Article
Language:English
Published: SAGE Publishing 2025-05-01
Series:SAGE Open Medical Case Reports
Online Access:https://doi.org/10.1177/2050313X251342989
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author Tasneem AbuShaikha
Saja Alzboun
Ameer Alhosheyeh
Imad Aljaafreh
Ahmad Alhalabia
Haytham Shaban
Ahmed Barbarawi
Yazan Haddar
Farah Awad
Elias Edward Lahham
author_facet Tasneem AbuShaikha
Saja Alzboun
Ameer Alhosheyeh
Imad Aljaafreh
Ahmad Alhalabia
Haytham Shaban
Ahmed Barbarawi
Yazan Haddar
Farah Awad
Elias Edward Lahham
author_sort Tasneem AbuShaikha
collection DOAJ
description Myoepithelial tumors are extremely rare tumors, with only about 30 cases reported in the literature to date. We present the case of a 27-year-old female diagnosed with malignant right fibula myoepithelial tumor/myoepithelial carcinoma, initially treated with systemic chemotherapy. During treatment, she developed uncontrolled leg pain and metastatic disease to the lungs, leading to a palliative above-knee amputation. Due to the rarity of malignant myoepithelial tumors and the lack of treatment guidelines, a systematic literature review was conducted, exploring various chemotherapeutic and biological agents. Her treatment was planned by a multidisciplinary team, considering her willingness to continue treatment, and ultimately, a decision was made to proceed with palliative care. This case report aims to provide valuable insights for physicians managing patients with this rare diagnosis.
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institution Kabale University
issn 2050-313X
language English
publishDate 2025-05-01
publisher SAGE Publishing
record_format Article
series SAGE Open Medical Case Reports
spelling doaj-art-6784a6b904344dd9b45ebbbb7e4d65a52025-08-20T03:48:15ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2025-05-011310.1177/2050313X251342989Malignant myoepithelial tumor of the right fibula in a young female: A case reportTasneem AbuShaikha0Saja Alzboun1Ameer Alhosheyeh2Imad Aljaafreh3Ahmad Alhalabia4Haytham Shaban5Ahmed Barbarawi6Yazan Haddar7Farah Awad8Elias Edward Lahham9Faculty of Medicine, Al-Quds University, Abu-Dis, PalestineFaculty of Medicine, Al-Quds University, Abu-Dis, PalestineFaculty of Medicine, Al-Quds University, Abu-Dis, PalestineFaculty of Medicine, Al-Quds University, Abu-Dis, PalestineFaculty of Medicine, Al-Quds University, Abu-Dis, PalestineFaculty of Medicine, Al-Quds University, Abu-Dis, PalestineFaculty of Medicine, Al-Quds University, Abu-Dis, PalestineFaculty of Medicine, Al-Quds University, Abu-Dis, PalestineDepartment of Oncology, Augusta Victoria Hospital, East Jerusalem, Palestinian Authority, PalestineDepartment of Radiation Oncology, Augusta Victoria Hospital, East Jerusalem, Palestinian Authority, PalestineMyoepithelial tumors are extremely rare tumors, with only about 30 cases reported in the literature to date. We present the case of a 27-year-old female diagnosed with malignant right fibula myoepithelial tumor/myoepithelial carcinoma, initially treated with systemic chemotherapy. During treatment, she developed uncontrolled leg pain and metastatic disease to the lungs, leading to a palliative above-knee amputation. Due to the rarity of malignant myoepithelial tumors and the lack of treatment guidelines, a systematic literature review was conducted, exploring various chemotherapeutic and biological agents. Her treatment was planned by a multidisciplinary team, considering her willingness to continue treatment, and ultimately, a decision was made to proceed with palliative care. This case report aims to provide valuable insights for physicians managing patients with this rare diagnosis.https://doi.org/10.1177/2050313X251342989
spellingShingle Tasneem AbuShaikha
Saja Alzboun
Ameer Alhosheyeh
Imad Aljaafreh
Ahmad Alhalabia
Haytham Shaban
Ahmed Barbarawi
Yazan Haddar
Farah Awad
Elias Edward Lahham
Malignant myoepithelial tumor of the right fibula in a young female: A case report
SAGE Open Medical Case Reports
title Malignant myoepithelial tumor of the right fibula in a young female: A case report
title_full Malignant myoepithelial tumor of the right fibula in a young female: A case report
title_fullStr Malignant myoepithelial tumor of the right fibula in a young female: A case report
title_full_unstemmed Malignant myoepithelial tumor of the right fibula in a young female: A case report
title_short Malignant myoepithelial tumor of the right fibula in a young female: A case report
title_sort malignant myoepithelial tumor of the right fibula in a young female a case report
url https://doi.org/10.1177/2050313X251342989
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