Malignant myoepithelial tumor of the right fibula in a young female: A case report

Myoepithelial tumors are extremely rare tumors, with only about 30 cases reported in the literature to date. We present the case of a 27-year-old female diagnosed with malignant right fibula myoepithelial tumor/myoepithelial carcinoma, initially treated with systemic chemotherapy. During treatment,...

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Main Authors: Tasneem AbuShaikha, Saja Alzboun, Ameer Alhosheyeh, Imad Aljaafreh, Ahmad Alhalabia, Haytham Shaban, Ahmed Barbarawi, Yazan Haddar, Farah Awad, Elias Edward Lahham
Format: Article
Language:English
Published: SAGE Publishing 2025-05-01
Series:SAGE Open Medical Case Reports
Online Access:https://doi.org/10.1177/2050313X251342989
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Summary:Myoepithelial tumors are extremely rare tumors, with only about 30 cases reported in the literature to date. We present the case of a 27-year-old female diagnosed with malignant right fibula myoepithelial tumor/myoepithelial carcinoma, initially treated with systemic chemotherapy. During treatment, she developed uncontrolled leg pain and metastatic disease to the lungs, leading to a palliative above-knee amputation. Due to the rarity of malignant myoepithelial tumors and the lack of treatment guidelines, a systematic literature review was conducted, exploring various chemotherapeutic and biological agents. Her treatment was planned by a multidisciplinary team, considering her willingness to continue treatment, and ultimately, a decision was made to proceed with palliative care. This case report aims to provide valuable insights for physicians managing patients with this rare diagnosis.
ISSN:2050-313X