Premonitory Urges and Sensorimotor Processing in Tourette Syndrome
Most patients with Tourette syndrome report characteristic sensory experiences (premonitory urges) associated with the expression of tic symptoms. Despite the central role of these experiences to the clinical phenomenology of Tourette syndrome, little is known about their underlying brain processes....
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Behavioural Neurology |
| Online Access: | http://dx.doi.org/10.3233/BEN-120308 |
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| _version_ | 1841524783754248192 |
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| author | Sangeerthana Rajagopal Stefano Seri Andrea Eugenio Cavanna |
| author_facet | Sangeerthana Rajagopal Stefano Seri Andrea Eugenio Cavanna |
| author_sort | Sangeerthana Rajagopal |
| collection | DOAJ |
| description | Most patients with Tourette syndrome report characteristic sensory experiences (premonitory urges) associated with the expression of tic symptoms. Despite the central role of these experiences to the clinical phenomenology of Tourette syndrome, little is known about their underlying brain processes. In the present article we present the results of a systematic literature review of the published studies addressing the pathophysiological mechanisms of premonitory urges. We identified some preliminary evidence for specific alterations in sensorimotor processing at both cortical and subcortical levels. A better insight into the brain correlates of premonitory urges could lead to the identification of new targets to treat the sensory initiators of tics in patients with Tourette syndrome. |
| format | Article |
| id | doaj-art-677cc600101541f387c915946e0bf7e9 |
| institution | Kabale University |
| issn | 0953-4180 1875-8584 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Behavioural Neurology |
| spelling | doaj-art-677cc600101541f387c915946e0bf7e92025-02-03T05:47:20ZengWileyBehavioural Neurology0953-41801875-85842013-01-01271657310.3233/BEN-120308Premonitory Urges and Sensorimotor Processing in Tourette SyndromeSangeerthana Rajagopal0Stefano Seri1Andrea Eugenio Cavanna2The Michael Trimble Neuropsychiatry Research Group, Department of Neuropsychiatry, BSMHFT and University of Birmingham, Birmingham, UKSchool of Life and Health Sciences, Aston Brain Centre, Aston University, Birmingham, UKThe Michael Trimble Neuropsychiatry Research Group, Department of Neuropsychiatry, BSMHFT and University of Birmingham, Birmingham, UKMost patients with Tourette syndrome report characteristic sensory experiences (premonitory urges) associated with the expression of tic symptoms. Despite the central role of these experiences to the clinical phenomenology of Tourette syndrome, little is known about their underlying brain processes. In the present article we present the results of a systematic literature review of the published studies addressing the pathophysiological mechanisms of premonitory urges. We identified some preliminary evidence for specific alterations in sensorimotor processing at both cortical and subcortical levels. A better insight into the brain correlates of premonitory urges could lead to the identification of new targets to treat the sensory initiators of tics in patients with Tourette syndrome.http://dx.doi.org/10.3233/BEN-120308 |
| spellingShingle | Sangeerthana Rajagopal Stefano Seri Andrea Eugenio Cavanna Premonitory Urges and Sensorimotor Processing in Tourette Syndrome Behavioural Neurology |
| title | Premonitory Urges and Sensorimotor Processing in Tourette Syndrome |
| title_full | Premonitory Urges and Sensorimotor Processing in Tourette Syndrome |
| title_fullStr | Premonitory Urges and Sensorimotor Processing in Tourette Syndrome |
| title_full_unstemmed | Premonitory Urges and Sensorimotor Processing in Tourette Syndrome |
| title_short | Premonitory Urges and Sensorimotor Processing in Tourette Syndrome |
| title_sort | premonitory urges and sensorimotor processing in tourette syndrome |
| url | http://dx.doi.org/10.3233/BEN-120308 |
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