Polysomnographic titration of non-invasive ventilation in motor neurone disease (3TLA): study protocol for a randomised controlled trial

Polysomnographic titration of non-invasive ventilation in motor neurone disease (3TLA): study protocol for a randomised controlled trial

Abstract Background Non-invasive ventilation (NIV) uses positive pressure to assist people with respiratory muscle weakness or severe respiratory compromise to breathe. Most people use this treatment during sleep when breathing is most susceptible to instability. The benefits of using NIV in motor n...

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Main Authors: David J. Berlowitz, Dominic Rowe, Mark E. Howard, Amanda Piper, Marnie Graco, Sabine Braat, Bhajan Singh, Tanara Viera Souza, Natasha Lannin, Alistair McLean, Abbey Sawyer, Kate A. Carey, Yasmin Ahamed, on behalf of the 3TLA Trial Group
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Trials
Subjects:
Motor neurone disease
Non-invasive ventilation
Polysomnography
Sleep study
Amyotrophic lateral sclerosis
Chronic respiratory failure
Online Access:https://doi.org/10.1186/s13063-024-08464-4
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