Network pharmacology integrated with experimental validation to elucidate the mechanisms of action of the Guizhi-Gancao Decoction in the treatment of phenylephrine-induced cardiac hypertrophy

Network pharmacology integrated with experimental validation to elucidate the mechanisms of action of the Guizhi-Gancao Decoction in the treatment of phenylephrine-induced cardiac hypertrophy

Context The mechanisms of Traditional Chinese Medicine (TCM) Guizhi-Gancao Decoction (GGD) remain unknown.Objective This study explores the mechanisms of GGD against cardiac hypertrophy.Materials and methods Network pharmacology analysis was carried out to identify the potential targets of GGD. In v...

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Bibliographic Details
Main Authors: Kaijing Yang, Xiaoli Shan, Yang Songru, Mengwei Fu, Pei Zhao, Wei Guo, Ming Xu, Huihua Chen, Rong Lu, Chen Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Pharmaceutical Biology
Subjects:
Heart failure
adenosine receptors
Traditional Chinese Medicine
Online Access:https://www.tandfonline.com/doi/10.1080/13880209.2024.2354335
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