P02 | THE C-C CHEMOKINE-RECEPTOR 2 (CCR2)/CCL2 AXIS PARTICIPATE IN PLATELET FUNCTION IN MYELOFIBROSIS
Myelofibrosis (MF) is the most severe myeloproliferative neoplasm driven by mutations of the MPL/JAK2 axis induced by megakaryocytes (MKs) with reduced GATA1 content1. The proinflammatory milieu in the bone marrow (BM) microenvironment favors the disease evolution, by sustaining BM fibrosis, hemato...
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| Format: | Article |
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| Language: | English |
| Published: |
PAGEPress Publications
2025-08-01
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| Series: | European Journal of Histochemistry |
| Subjects: | |
| Online Access: | https://www.ejh.it/ejh/article/view/4322 |
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