Influences of physical stimulations on the migration and differentiation of Schwann cells involved in peripheral nerve repair
Peripheral nerve injury repair has always been a research concern of scientists. At the tissue level, axonal regeneration has become a research spotlight in peripheral nerve repair. Through transplantation of autologous nerve grafts or other emerging biomaterials functional recovery after facial ner...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2025-12-01
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| Series: | Cell Adhesion & Migration |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/19336918.2025.2450311 |
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| author | Qingyan Sun Xiaodan Mu Qi Gao Juncheng Wang Min Hu Huawei Liu |
| author_facet | Qingyan Sun Xiaodan Mu Qi Gao Juncheng Wang Min Hu Huawei Liu |
| author_sort | Qingyan Sun |
| collection | DOAJ |
| description | Peripheral nerve injury repair has always been a research concern of scientists. At the tissue level, axonal regeneration has become a research spotlight in peripheral nerve repair. Through transplantation of autologous nerve grafts or other emerging biomaterials functional recovery after facial nerve injury is not ideal in clinical scenarios. Great strides have been made to improve facial nerve repair at the micro-cellular level. Physical stimulation techniques can trigger Schwann cells (SCs) to migrate and differentiate into cells required for peripheral nerve repair. Classified by the sources of physical stimulations, SCs repair peripheral nerves through galvanotaxis, magnetotaxis and durotaxis. This article summarized the activation, directional migration and differentiation of SCs induced by physical stimulations, thus providing new ideas for the research of peripheral nerve repair. |
| format | Article |
| id | doaj-art-65e2231e24044037ba7f50b4d8a3c49b |
| institution | Kabale University |
| issn | 1933-6918 1933-6926 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Cell Adhesion & Migration |
| spelling | doaj-art-65e2231e24044037ba7f50b4d8a3c49b2025-01-16T10:08:49ZengTaylor & Francis GroupCell Adhesion & Migration1933-69181933-69262025-12-0119110.1080/19336918.2025.2450311Influences of physical stimulations on the migration and differentiation of Schwann cells involved in peripheral nerve repairQingyan Sun0Xiaodan MuQi Gao1Juncheng Wang2Min Hu3Huawei Liu4Department of Stomatology, The First Medical Center, Chinese PLA General Hospital, Beijing, ChinaDepartment of Stomatology of Air Force Hospital in the Southern Theater, Guangzhou, Guangdong Province, ChinaDepartment of Stomatology, The First Medical Center, Chinese PLA General Hospital, Beijing, ChinaDepartment of Stomatology, The First Medical Center, Chinese PLA General Hospital, Beijing, ChinaDepartment of Stomatology, The First Medical Center, Chinese PLA General Hospital, Beijing, ChinaPeripheral nerve injury repair has always been a research concern of scientists. At the tissue level, axonal regeneration has become a research spotlight in peripheral nerve repair. Through transplantation of autologous nerve grafts or other emerging biomaterials functional recovery after facial nerve injury is not ideal in clinical scenarios. Great strides have been made to improve facial nerve repair at the micro-cellular level. Physical stimulation techniques can trigger Schwann cells (SCs) to migrate and differentiate into cells required for peripheral nerve repair. Classified by the sources of physical stimulations, SCs repair peripheral nerves through galvanotaxis, magnetotaxis and durotaxis. This article summarized the activation, directional migration and differentiation of SCs induced by physical stimulations, thus providing new ideas for the research of peripheral nerve repair.https://www.tandfonline.com/doi/10.1080/19336918.2025.2450311Durotaxisgalvanotaxismagnetotaxisperipheral nerve repairSchwann cells |
| spellingShingle | Qingyan Sun Xiaodan Mu Qi Gao Juncheng Wang Min Hu Huawei Liu Influences of physical stimulations on the migration and differentiation of Schwann cells involved in peripheral nerve repair Cell Adhesion & Migration Durotaxis galvanotaxis magnetotaxis peripheral nerve repair Schwann cells |
| title | Influences of physical stimulations on the migration and differentiation of Schwann cells involved in peripheral nerve repair |
| title_full | Influences of physical stimulations on the migration and differentiation of Schwann cells involved in peripheral nerve repair |
| title_fullStr | Influences of physical stimulations on the migration and differentiation of Schwann cells involved in peripheral nerve repair |
| title_full_unstemmed | Influences of physical stimulations on the migration and differentiation of Schwann cells involved in peripheral nerve repair |
| title_short | Influences of physical stimulations on the migration and differentiation of Schwann cells involved in peripheral nerve repair |
| title_sort | influences of physical stimulations on the migration and differentiation of schwann cells involved in peripheral nerve repair |
| topic | Durotaxis galvanotaxis magnetotaxis peripheral nerve repair Schwann cells |
| url | https://www.tandfonline.com/doi/10.1080/19336918.2025.2450311 |
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