Successful Diagnosis and Management of Superior Orbital Fissure Syndrome Secondary to Lung Adenocarcinoma: A Case Report

Yufang Wang, Xiangrong Zhao Department of Radiotherapy, Liaocheng Hospital Affiliated to Shandong First Medical University (Liaocheng People’s Hospital), Liaocheng, Shandong, People’s Republic of ChinaCorrespondence: Xiangrong Zhao, Email zxrzai@163.comIntroduction: Superior orbital fissure syndrome...

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Main Authors: Wang Y, Zhao X
Format: Article
Language:English
Published: Dove Medical Press 2025-01-01
Series:Cancer Management and Research
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Online Access:https://www.dovepress.com/successful-diagnosis-and-management-of-superior-orbital-fissure-syndro-peer-reviewed-fulltext-article-CMAR
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author Wang Y
Zhao X
author_facet Wang Y
Zhao X
author_sort Wang Y
collection DOAJ
description Yufang Wang, Xiangrong Zhao Department of Radiotherapy, Liaocheng Hospital Affiliated to Shandong First Medical University (Liaocheng People’s Hospital), Liaocheng, Shandong, People’s Republic of ChinaCorrespondence: Xiangrong Zhao, Email zxrzai@163.comIntroduction: Superior orbital fissure syndrome (SOFS) is a rare condition that involves damage to multiple structures within the superior orbital fissure, often caused by trauma, inflammation, or tumors. Lung adenocarcinoma, known for its propensity to metastasize, can lead to orbital metastases, which can manifest as SOFS. This case underscores the diagnostic and therapeutic challenges associated with such rare metastatic presentations.Case Presentation: A 60-year-old woman with a history of left lung adenocarcinoma presented with left eyelid ptosis and fixed eye position following hair dyeing. Despite initial treatments and imaging, her condition persisted. Subsequent imaging and thorough clinical evaluation revealed metastasis to the left superior orbital fissure. The patient was treated with volumetric modulated arc therapy (VMAT), leading to significant clinical improvement and reduction of the orbital mass.Conclusion: This case highlights the critical role of comprehensive diagnostic evaluation and communication between specialists in managing rare metastatic conditions. It also demonstrates the efficacy of localized radiotherapy in treating such uncommon presentations of lung cancer metastasis.Keywords: superior orbital fissure syndrome, lung adenocarcinoma, metastasis, radiotherapy, case report
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series Cancer Management and Research
spelling doaj-art-659c869b482f48f38a435a7b98ae1a7e2025-01-16T16:17:12ZengDove Medical PressCancer Management and Research1179-13222025-01-01Volume 17576399258Successful Diagnosis and Management of Superior Orbital Fissure Syndrome Secondary to Lung Adenocarcinoma: A Case ReportWang YZhao XYufang Wang, Xiangrong Zhao Department of Radiotherapy, Liaocheng Hospital Affiliated to Shandong First Medical University (Liaocheng People’s Hospital), Liaocheng, Shandong, People’s Republic of ChinaCorrespondence: Xiangrong Zhao, Email zxrzai@163.comIntroduction: Superior orbital fissure syndrome (SOFS) is a rare condition that involves damage to multiple structures within the superior orbital fissure, often caused by trauma, inflammation, or tumors. Lung adenocarcinoma, known for its propensity to metastasize, can lead to orbital metastases, which can manifest as SOFS. This case underscores the diagnostic and therapeutic challenges associated with such rare metastatic presentations.Case Presentation: A 60-year-old woman with a history of left lung adenocarcinoma presented with left eyelid ptosis and fixed eye position following hair dyeing. Despite initial treatments and imaging, her condition persisted. Subsequent imaging and thorough clinical evaluation revealed metastasis to the left superior orbital fissure. The patient was treated with volumetric modulated arc therapy (VMAT), leading to significant clinical improvement and reduction of the orbital mass.Conclusion: This case highlights the critical role of comprehensive diagnostic evaluation and communication between specialists in managing rare metastatic conditions. It also demonstrates the efficacy of localized radiotherapy in treating such uncommon presentations of lung cancer metastasis.Keywords: superior orbital fissure syndrome, lung adenocarcinoma, metastasis, radiotherapy, case reporthttps://www.dovepress.com/successful-diagnosis-and-management-of-superior-orbital-fissure-syndro-peer-reviewed-fulltext-article-CMARsuperior orbital fissure syndromelung adenocarcinomametastasisradiotherapycase report
spellingShingle Wang Y
Zhao X
Successful Diagnosis and Management of Superior Orbital Fissure Syndrome Secondary to Lung Adenocarcinoma: A Case Report
Cancer Management and Research
superior orbital fissure syndrome
lung adenocarcinoma
metastasis
radiotherapy
case report
title Successful Diagnosis and Management of Superior Orbital Fissure Syndrome Secondary to Lung Adenocarcinoma: A Case Report
title_full Successful Diagnosis and Management of Superior Orbital Fissure Syndrome Secondary to Lung Adenocarcinoma: A Case Report
title_fullStr Successful Diagnosis and Management of Superior Orbital Fissure Syndrome Secondary to Lung Adenocarcinoma: A Case Report
title_full_unstemmed Successful Diagnosis and Management of Superior Orbital Fissure Syndrome Secondary to Lung Adenocarcinoma: A Case Report
title_short Successful Diagnosis and Management of Superior Orbital Fissure Syndrome Secondary to Lung Adenocarcinoma: A Case Report
title_sort successful diagnosis and management of superior orbital fissure syndrome secondary to lung adenocarcinoma a case report
topic superior orbital fissure syndrome
lung adenocarcinoma
metastasis
radiotherapy
case report
url https://www.dovepress.com/successful-diagnosis-and-management-of-superior-orbital-fissure-syndro-peer-reviewed-fulltext-article-CMAR
work_keys_str_mv AT wangy successfuldiagnosisandmanagementofsuperiororbitalfissuresyndromesecondarytolungadenocarcinomaacasereport
AT zhaox successfuldiagnosisandmanagementofsuperiororbitalfissuresyndromesecondarytolungadenocarcinomaacasereport