Mucosal-adapted bacteriophages as a preventive strategy for a lethal Pseudomonas aeruginosa challenge in mice

Mucosal-adapted bacteriophages as a preventive strategy for a lethal Pseudomonas aeruginosa challenge in mice

Abstract Pseudomonas aeruginosa is an emergent threat due to the antimicrobial resistance crisis. Bacteriophages (phages) are promising agents for phage therapy approaches against P. aeruginosa. It has been proposed that metazoans harbor phages on their mucosal surfaces, and this could be exploited...

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Main Authors: Luiz Felipe Leomil Coelho, Mateus de Souza Terceti, Sergio Pereira Lima Neto, Raíne Piva Amaral, Ana Luisa Cauvila dos Santos, William Permagnani Gozzi, Bianca Andrade de Carvalho, Gustavo Aparecido da Cunha, Maria Fernanda Romboli Durante, Lais Sanchietta, Giovana Soares Marangoni, Matheus Luca Carotta Gabriel, Luiz Cosme Cotta Malaquias, Eliana Leonor Hurtado Celis, Giovanna de Souza Apolinário, João Pessoa Araujo Junior, Carine Ervolino de Oliveira, Victoria Fulgencio Queiroz, Gabriel Magno de Freitas Almeida
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-07269-0
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