Red blood cell storage lesion: a progress review

Red blood cells are the main mediators of oxygen transportation in the body. Under normal conditions, the life span of red blood cells circulating in the human body is approximately 120 days. However, after blood donation, erythrocytes in the storage process will eventually induce the occurrence of...

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Main Authors: CHEN Cheng, XIA Rong
Format: Article
Language:zho
Published: Institute of Blood Transfusion of Chinese Academy of Medical Sciences 2024-12-01
Series:Zhongguo shuxue zazhi
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Online Access:https://www.cjbt.cn/thesisDetails#10.13303/j.cjbt.issn.1004-549x.2024.12.017&lang=en
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author CHEN Cheng
XIA Rong
author_facet CHEN Cheng
XIA Rong
author_sort CHEN Cheng
collection DOAJ
description Red blood cells are the main mediators of oxygen transportation in the body. Under normal conditions, the life span of red blood cells circulating in the human body is approximately 120 days. However, after blood donation, erythrocytes in the storage process will eventually induce the occurrence of storage injury due to the accumulation or consumption of metabolites. This review presents a summary of recent research on the mechanism of red blood cell storage lesion, its potential clinical effects and corresponding strategies as follows.
format Article
id doaj-art-654ccd40285147499d71985b6496599c
institution Kabale University
issn 1004-549X
language zho
publishDate 2024-12-01
publisher Institute of Blood Transfusion of Chinese Academy of Medical Sciences
record_format Article
series Zhongguo shuxue zazhi
spelling doaj-art-654ccd40285147499d71985b6496599c2025-01-06T09:43:02ZzhoInstitute of Blood Transfusion of Chinese Academy of Medical SciencesZhongguo shuxue zazhi1004-549X2024-12-0137121445144910.13303/j.cjbt.issn.1004-549x.2024.12.0171004-549X(2024)12-1445-05Red blood cell storage lesion: a progress reviewCHEN Cheng0XIA Rong1Department of Transfusion, Huashan Hospital, Fudan University, Shanghai 200040, ChinaDepartment of Transfusion, Huashan Hospital, Fudan University, Shanghai 200040, ChinaRed blood cells are the main mediators of oxygen transportation in the body. Under normal conditions, the life span of red blood cells circulating in the human body is approximately 120 days. However, after blood donation, erythrocytes in the storage process will eventually induce the occurrence of storage injury due to the accumulation or consumption of metabolites. This review presents a summary of recent research on the mechanism of red blood cell storage lesion, its potential clinical effects and corresponding strategies as follows.https://www.cjbt.cn/thesisDetails#10.13303/j.cjbt.issn.1004-549x.2024.12.017&lang=enred blood cell storage lesionred blood cell transfusiontransfusion-related immunomodulation
spellingShingle CHEN Cheng
XIA Rong
Red blood cell storage lesion: a progress review
Zhongguo shuxue zazhi
red blood cell storage lesion
red blood cell transfusion
transfusion-related immunomodulation
title Red blood cell storage lesion: a progress review
title_full Red blood cell storage lesion: a progress review
title_fullStr Red blood cell storage lesion: a progress review
title_full_unstemmed Red blood cell storage lesion: a progress review
title_short Red blood cell storage lesion: a progress review
title_sort red blood cell storage lesion a progress review
topic red blood cell storage lesion
red blood cell transfusion
transfusion-related immunomodulation
url https://www.cjbt.cn/thesisDetails#10.13303/j.cjbt.issn.1004-549x.2024.12.017&lang=en
work_keys_str_mv AT chencheng redbloodcellstoragelesionaprogressreview
AT xiarong redbloodcellstoragelesionaprogressreview