Detection of Rare Weaker A Subgroup: Aend
Subgroups of A are very rare phenotypes. Weaker subgroups give rise to discrepancies between forward and reverse grouping. Conventional methods could misread these rare and weak subgroups occasionally. Weaker A subgroups that have been reported so far are mainly A3, Ax, Aend, Am, Ay, and Ael. Here,...
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| Main Author: | |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2024-11-01
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| Series: | Global Journal of Transfusion Medicine |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/gjtm.gjtm_35_24 |
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| Summary: | Subgroups of A are very rare phenotypes. Weaker subgroups give rise to discrepancies between forward and reverse grouping. Conventional methods could misread these rare and weak subgroups occasionally. Weaker A subgroups that have been reported so far are mainly A3, Ax, Aend, Am, Ay, and Ael. Here, we report one interesting case of a rare weaker A subgroup in a patient who was wrongly typed as Group O. After performing the initial blood grouping, a detailed analysis was done including absorption elution tests and saliva tests. The serological characteristics of the patient’s red cells were similar to the Aend subtype. The patient was a secretor having only H substance. Anti-A1 was absent in the serum. This report highlights the importance of routine forward and reverse grouping in solving blood group discrepancy. |
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| ISSN: | 2468-8398 2455-8893 |