Successful management of Leydig Cell Tumor in a 65-year-Old patient: A rare case report
Leydig cell tumors (LCTs) are rare testicular neoplasms, representing 1–3% of all testicular tumors. A 65-year-old male presented with a painless left scrotal mass. Ultrasound revealed a 61 × 53 × 35 mm tumor with heterogeneous echogenicity and abundant blood supply. Radical orchidectomy was perform...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-01-01
|
| Series: | Urology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S221444202400281X |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841542455374118912 |
|---|---|
| author | Hasan Haydar Ayham Qatza Saja Karaja Anagheem Alkhleef Mohamad Yasin Lutfi Habib Jarbouh |
| author_facet | Hasan Haydar Ayham Qatza Saja Karaja Anagheem Alkhleef Mohamad Yasin Lutfi Habib Jarbouh |
| author_sort | Hasan Haydar |
| collection | DOAJ |
| description | Leydig cell tumors (LCTs) are rare testicular neoplasms, representing 1–3% of all testicular tumors. A 65-year-old male presented with a painless left scrotal mass. Ultrasound revealed a 61 × 53 × 35 mm tumor with heterogeneous echogenicity and abundant blood supply. Radical orchidectomy was performed, and immunohistochemistry confirmed LCT with positivity for Inhibin A and calretinin, and negativity for CK, chromogranin, LCA, and low Ki67. Postoperative follow-up at 6 months showed improved condition, no scrotal masses, and normal tumor markers. Finally, LCTs in older males require differential diagnosis; hormonal activity impacts presentation. Conservative management and monitoring are crucial. |
| format | Article |
| id | doaj-art-64ef037dc88740e59a829c026cd53805 |
| institution | Kabale University |
| issn | 2214-4420 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Urology Case Reports |
| spelling | doaj-art-64ef037dc88740e59a829c026cd538052025-01-14T04:12:23ZengElsevierUrology Case Reports2214-44202025-01-0158102927Successful management of Leydig Cell Tumor in a 65-year-Old patient: A rare case reportHasan Haydar0Ayham Qatza1Saja Karaja2Anagheem Alkhleef3Mohamad Yasin Lutfi4Habib Jarbouh5Faculty of Medicine, Hama University, Hama, Syrian Arab Republic; Corresponding author.Faculty of Medicine, Hama University, Hama, Syrian Arab RepublicFaculty of Medicine, Hama University, Hama, Syrian Arab RepublicHama National Hospital, Internal Medicine Department, Hama, Syrian Arab RepublicHama National Hospital, Urology Department, Hama, Syrian Arab RepublicFaculty member, Faculty of Medicine, Pathology Department, Damascus University, Damascus, Syrian Arab RepublicLeydig cell tumors (LCTs) are rare testicular neoplasms, representing 1–3% of all testicular tumors. A 65-year-old male presented with a painless left scrotal mass. Ultrasound revealed a 61 × 53 × 35 mm tumor with heterogeneous echogenicity and abundant blood supply. Radical orchidectomy was performed, and immunohistochemistry confirmed LCT with positivity for Inhibin A and calretinin, and negativity for CK, chromogranin, LCA, and low Ki67. Postoperative follow-up at 6 months showed improved condition, no scrotal masses, and normal tumor markers. Finally, LCTs in older males require differential diagnosis; hormonal activity impacts presentation. Conservative management and monitoring are crucial.http://www.sciencedirect.com/science/article/pii/S221444202400281XLeydig cell tumorTesticular neoplasmsRadical orchidectomyCase report |
| spellingShingle | Hasan Haydar Ayham Qatza Saja Karaja Anagheem Alkhleef Mohamad Yasin Lutfi Habib Jarbouh Successful management of Leydig Cell Tumor in a 65-year-Old patient: A rare case report Urology Case Reports Leydig cell tumor Testicular neoplasms Radical orchidectomy Case report |
| title | Successful management of Leydig Cell Tumor in a 65-year-Old patient: A rare case report |
| title_full | Successful management of Leydig Cell Tumor in a 65-year-Old patient: A rare case report |
| title_fullStr | Successful management of Leydig Cell Tumor in a 65-year-Old patient: A rare case report |
| title_full_unstemmed | Successful management of Leydig Cell Tumor in a 65-year-Old patient: A rare case report |
| title_short | Successful management of Leydig Cell Tumor in a 65-year-Old patient: A rare case report |
| title_sort | successful management of leydig cell tumor in a 65 year old patient a rare case report |
| topic | Leydig cell tumor Testicular neoplasms Radical orchidectomy Case report |
| url | http://www.sciencedirect.com/science/article/pii/S221444202400281X |
| work_keys_str_mv | AT hasanhaydar successfulmanagementofleydigcelltumorina65yearoldpatientararecasereport AT ayhamqatza successfulmanagementofleydigcelltumorina65yearoldpatientararecasereport AT sajakaraja successfulmanagementofleydigcelltumorina65yearoldpatientararecasereport AT anagheemalkhleef successfulmanagementofleydigcelltumorina65yearoldpatientararecasereport AT mohamadyasinlutfi successfulmanagementofleydigcelltumorina65yearoldpatientararecasereport AT habibjarbouh successfulmanagementofleydigcelltumorina65yearoldpatientararecasereport |