Successful management of Leydig Cell Tumor in a 65-year-Old patient: A rare case report

Leydig cell tumors (LCTs) are rare testicular neoplasms, representing 1–3% of all testicular tumors. A 65-year-old male presented with a painless left scrotal mass. Ultrasound revealed a 61 × 53 × 35 mm tumor with heterogeneous echogenicity and abundant blood supply. Radical orchidectomy was perform...

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Bibliographic Details
Main Authors: Hasan Haydar, Ayham Qatza, Saja Karaja, Anagheem Alkhleef, Mohamad Yasin Lutfi, Habib Jarbouh
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Urology Case Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S221444202400281X
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Summary:Leydig cell tumors (LCTs) are rare testicular neoplasms, representing 1–3% of all testicular tumors. A 65-year-old male presented with a painless left scrotal mass. Ultrasound revealed a 61 × 53 × 35 mm tumor with heterogeneous echogenicity and abundant blood supply. Radical orchidectomy was performed, and immunohistochemistry confirmed LCT with positivity for Inhibin A and calretinin, and negativity for CK, chromogranin, LCA, and low Ki67. Postoperative follow-up at 6 months showed improved condition, no scrotal masses, and normal tumor markers. Finally, LCTs in older males require differential diagnosis; hormonal activity impacts presentation. Conservative management and monitoring are crucial.
ISSN:2214-4420