Efficacy of plant extract in chronic low back pain: A meta-analysis

Background: Chronic low back pain (CLBP) impacts quality of life and healthcare reliance. Objectives: We systematically reviewed randomized controlled trials (RCTs) on the use of plant extracts to treat CLBP according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelin...

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Main Authors: Chen-Pi Li, Ru-Yin Tsai, Jui-Ting Yu, Shin-Chuan Huang, Fang-Ling Liu, Sheng-Yi Lin
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Tungs’ Medical Journal
Subjects:
Online Access:https://doi.org/10.4103/ETMJ.ETMJ-D-24-00025
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author Chen-Pi Li
Ru-Yin Tsai
Jui-Ting Yu
Shin-Chuan Huang
Fang-Ling Liu
Sheng-Yi Lin
author_facet Chen-Pi Li
Ru-Yin Tsai
Jui-Ting Yu
Shin-Chuan Huang
Fang-Ling Liu
Sheng-Yi Lin
author_sort Chen-Pi Li
collection DOAJ
description Background: Chronic low back pain (CLBP) impacts quality of life and healthcare reliance. Objectives: We systematically reviewed randomized controlled trials (RCTs) on the use of plant extracts to treat CLBP according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. Methods: Four databases (i.e., PubMed, Scopus, Web of Science, and The Cochrane Library) were searched for published studies. We searched databases up to July 2024. Seven RCTs were analyzed. The study has been registered in PROSPERO (number: CRD 42024570674). Results: Plant extracts alone or combined with massage significantly reduced pain, particularly when applied to multiple meridian points. Conclusion: Plant extracts are a promising nonpharmacological treatment option for CLBP. One potential mechanism is through their interaction with multiple meridian pathways, which may enhance pain relief. This possible relationship between meridian involvement and therapeutic efficacy warrants further investigation to better understand the long-term benefits and underlying mechanisms of plant extract therapy.
format Article
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institution Kabale University
issn 2071-3592
2949-9720
language English
publishDate 2024-12-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Tungs’ Medical Journal
spelling doaj-art-64b3b689bcb9431e891061b10dfb78702025-01-17T10:57:17ZengWolters Kluwer Medknow PublicationsTungs’ Medical Journal2071-35922949-97202024-12-011829210110.4103/ETMJ.ETMJ-D-24-00025Efficacy of plant extract in chronic low back pain: A meta-analysisChen-Pi LiRu-Yin TsaiJui-Ting YuShin-Chuan HuangFang-Ling LiuSheng-Yi LinBackground: Chronic low back pain (CLBP) impacts quality of life and healthcare reliance. Objectives: We systematically reviewed randomized controlled trials (RCTs) on the use of plant extracts to treat CLBP according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. Methods: Four databases (i.e., PubMed, Scopus, Web of Science, and The Cochrane Library) were searched for published studies. We searched databases up to July 2024. Seven RCTs were analyzed. The study has been registered in PROSPERO (number: CRD 42024570674). Results: Plant extracts alone or combined with massage significantly reduced pain, particularly when applied to multiple meridian points. Conclusion: Plant extracts are a promising nonpharmacological treatment option for CLBP. One potential mechanism is through their interaction with multiple meridian pathways, which may enhance pain relief. This possible relationship between meridian involvement and therapeutic efficacy warrants further investigation to better understand the long-term benefits and underlying mechanisms of plant extract therapy.https://doi.org/10.4103/ETMJ.ETMJ-D-24-00025aromatherapybotanicalchronic painherbmassagemeridian entry
spellingShingle Chen-Pi Li
Ru-Yin Tsai
Jui-Ting Yu
Shin-Chuan Huang
Fang-Ling Liu
Sheng-Yi Lin
Efficacy of plant extract in chronic low back pain: A meta-analysis
Tungs’ Medical Journal
aromatherapy
botanical
chronic pain
herb
massage
meridian entry
title Efficacy of plant extract in chronic low back pain: A meta-analysis
title_full Efficacy of plant extract in chronic low back pain: A meta-analysis
title_fullStr Efficacy of plant extract in chronic low back pain: A meta-analysis
title_full_unstemmed Efficacy of plant extract in chronic low back pain: A meta-analysis
title_short Efficacy of plant extract in chronic low back pain: A meta-analysis
title_sort efficacy of plant extract in chronic low back pain a meta analysis
topic aromatherapy
botanical
chronic pain
herb
massage
meridian entry
url https://doi.org/10.4103/ETMJ.ETMJ-D-24-00025
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