Vitamin D Level in Postmenopausal Breast Cancer Patients Before and After Adjuvant Chemotherapy and Endocrine Therapy
Background: Deficiency of vitamin D is associated with the risk of the development of several cancers. Objective: This study aimed to verify the effect of the adjuvant chemotherapy and hormonal therapy on the vitamin D level in breast cancer patients. Materials and Methods: This is a prospective cas...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | Medical Journal of Babylon |
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| Online Access: | https://doi.org/10.4103/MJBL.MJBL_399_23 |
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| _version_ | 1841525456748150784 |
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| author | Barrak F. Al Obeidy Alya A. Al Zobair Mohammed A. Hayawi |
| author_facet | Barrak F. Al Obeidy Alya A. Al Zobair Mohammed A. Hayawi |
| author_sort | Barrak F. Al Obeidy |
| collection | DOAJ |
| description | Background: Deficiency of vitamin D is associated with the risk of the development of several cancers. Objective: This study aimed to verify the effect of the adjuvant chemotherapy and hormonal therapy on the vitamin D level in breast cancer patients. Materials and Methods: This is a prospective case–control study consisting of 65 postmenopausal patients with breast cancers compared to 40 postmenopausal control women from Nineveh province, vitamin D level was measured at the time of the diagnosis; immediately after the completion of adjuvant chemotherapy and 6 months after completing chemotherapy attending Mosul oncology Hospital during 2017–2019. Results: The present study demonstrated that vitamin D level at the time of diagnosis was lower in patients group compared with the control group. After the completion of adjuvant chemotherapy, the mean value of vitamin D level was significantly lower than the mean value of vitamin D level at the time of diagnosis. Six months after finishing chemotherapy, the value of vitamin D level was slightly recovered but still significantly lower than the mean value of vitamin D level at the time of diagnosis of breast cancer patients. Conclusion: Vitamin D deficiency seems common among breast cancer patients in Nineveh province, which became more prominent after giving chemotherapy. |
| format | Article |
| id | doaj-art-64b15ef3e4a74325b9dd06e0d7a07ca7 |
| institution | Kabale University |
| issn | 1812-156X 2312-6760 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Medical Journal of Babylon |
| spelling | doaj-art-64b15ef3e4a74325b9dd06e0d7a07ca72025-01-17T10:54:57ZengWolters Kluwer Medknow PublicationsMedical Journal of Babylon1812-156X2312-67602024-12-0121490991410.4103/MJBL.MJBL_399_23Vitamin D Level in Postmenopausal Breast Cancer Patients Before and After Adjuvant Chemotherapy and Endocrine TherapyBarrak F. Al ObeidyAlya A. Al ZobairMohammed A. HayawiBackground: Deficiency of vitamin D is associated with the risk of the development of several cancers. Objective: This study aimed to verify the effect of the adjuvant chemotherapy and hormonal therapy on the vitamin D level in breast cancer patients. Materials and Methods: This is a prospective case–control study consisting of 65 postmenopausal patients with breast cancers compared to 40 postmenopausal control women from Nineveh province, vitamin D level was measured at the time of the diagnosis; immediately after the completion of adjuvant chemotherapy and 6 months after completing chemotherapy attending Mosul oncology Hospital during 2017–2019. Results: The present study demonstrated that vitamin D level at the time of diagnosis was lower in patients group compared with the control group. After the completion of adjuvant chemotherapy, the mean value of vitamin D level was significantly lower than the mean value of vitamin D level at the time of diagnosis. Six months after finishing chemotherapy, the value of vitamin D level was slightly recovered but still significantly lower than the mean value of vitamin D level at the time of diagnosis of breast cancer patients. Conclusion: Vitamin D deficiency seems common among breast cancer patients in Nineveh province, which became more prominent after giving chemotherapy.https://doi.org/10.4103/MJBL.MJBL_399_23breast cancerchemotherapyhormonal therapyvitamin d |
| spellingShingle | Barrak F. Al Obeidy Alya A. Al Zobair Mohammed A. Hayawi Vitamin D Level in Postmenopausal Breast Cancer Patients Before and After Adjuvant Chemotherapy and Endocrine Therapy Medical Journal of Babylon breast cancer chemotherapy hormonal therapy vitamin d |
| title | Vitamin D Level in Postmenopausal Breast Cancer Patients Before and After Adjuvant Chemotherapy and Endocrine Therapy |
| title_full | Vitamin D Level in Postmenopausal Breast Cancer Patients Before and After Adjuvant Chemotherapy and Endocrine Therapy |
| title_fullStr | Vitamin D Level in Postmenopausal Breast Cancer Patients Before and After Adjuvant Chemotherapy and Endocrine Therapy |
| title_full_unstemmed | Vitamin D Level in Postmenopausal Breast Cancer Patients Before and After Adjuvant Chemotherapy and Endocrine Therapy |
| title_short | Vitamin D Level in Postmenopausal Breast Cancer Patients Before and After Adjuvant Chemotherapy and Endocrine Therapy |
| title_sort | vitamin d level in postmenopausal breast cancer patients before and after adjuvant chemotherapy and endocrine therapy |
| topic | breast cancer chemotherapy hormonal therapy vitamin d |
| url | https://doi.org/10.4103/MJBL.MJBL_399_23 |
| work_keys_str_mv | AT barrakfalobeidy vitamindlevelinpostmenopausalbreastcancerpatientsbeforeandafteradjuvantchemotherapyandendocrinetherapy AT alyaaalzobair vitamindlevelinpostmenopausalbreastcancerpatientsbeforeandafteradjuvantchemotherapyandendocrinetherapy AT mohammedahayawi vitamindlevelinpostmenopausalbreastcancerpatientsbeforeandafteradjuvantchemotherapyandendocrinetherapy |