Ultra-small curcumin-ruthenium coordination polymer nanodots prevent renal ischemia-reperfusion injury and the progression to chronic kidney disease

Ultra-small curcumin-ruthenium coordination polymer nanodots prevent renal ischemia-reperfusion injury and the progression to chronic kidney disease

Renal ischemia-reperfusion (IR) induces tissue hypoxia, resulting in disrupted energy metabolism and heightened oxidative stress. These factors contribute to tubular cell damage, which is a leading cause of acute kidney injury (AKI) and can progress to chronic kidney disease (CKD). The excessive gen...

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Bibliographic Details
Main Authors: Xian Liu, Qin Yu, Hai-Bo Mao, Jing-Bo Hu, Wei-Hua Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
acute kidney injury
chronic kidney disease
ischemia-reperfusion
curcumin
ruthenium
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2024.1506909/full
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