The influence of epicardial adipose tissue on the prognosis of atrial fibrillation patients undergoing radiofrequency ablation combined with left atrial appendage occlusion
Abstract Atrial fibrillation is the most common arrhythmia in adults. The interplay between epicardial adipose tissue and atrial fibrillation has garnered significant scientific interest. Recently, the combined approach of radiofrequency ablation and left atrial appendage occlusion has become a wide...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2024-11-01
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| Series: | Scientific Reports |
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| Online Access: | https://doi.org/10.1038/s41598-024-79873-3 |
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| author | Yuefeng Ju MaoJing Wang Yang Ji Zhihui Wang Wenzhuo Wang Feiyue Liu Siqi Yin Qing Zhao |
| author_facet | Yuefeng Ju MaoJing Wang Yang Ji Zhihui Wang Wenzhuo Wang Feiyue Liu Siqi Yin Qing Zhao |
| author_sort | Yuefeng Ju |
| collection | DOAJ |
| description | Abstract Atrial fibrillation is the most common arrhythmia in adults. The interplay between epicardial adipose tissue and atrial fibrillation has garnered significant scientific interest. Recently, the combined approach of radiofrequency ablation and left atrial appendage occlusion has become a widely adopted strategy for managing non-valvular atrial fibrillation patients at high risk of thrombus formation. This study aims to assess the prognostic significance of epicardial adipose tissue volume in patients undergoing radiofrequency ablation in conjunction with left atrial appendage occlusion. This study results indicate that in patients undergoing the one-stop procedure, which comprises catheter radiofrequency ablation and percutaneous left atrial appendage occlusion, epicardial adipose tissue volume is significantly associated with AF recurrence post-strategy. Higher EATV predicts AF recurrence (HR = 1.17, 95%CI1.047-1.192, P = 0.001) and thromboembolism (P = 0.002) following the one-stop procedure. Epicardial adipose tissue volume serves as a significant predictor of atrial fibrillation recurrence following the one-stop procedure (area under the curve 0.648, 95%CI0.571-0.725, P = 0.002, sensitivity 0.88, specificity 0.50). |
| format | Article |
| id | doaj-art-64747d8c2aef47da85a59df05f4f6056 |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-64747d8c2aef47da85a59df05f4f60562024-11-17T12:26:07ZengNature PortfolioScientific Reports2045-23222024-11-0114111310.1038/s41598-024-79873-3The influence of epicardial adipose tissue on the prognosis of atrial fibrillation patients undergoing radiofrequency ablation combined with left atrial appendage occlusionYuefeng Ju0MaoJing Wang1Yang Ji2Zhihui Wang3Wenzhuo Wang4Feiyue Liu5Siqi Yin6Qing Zhao7The Affiliated Hospital of Qingdao UniversityThe Affiliated Hospital of Qingdao UniversityThe Affiliated Hospital of Qingdao UniversityThe Affiliated Hospital of Qingdao UniversityThe Affiliated Hospital of Qingdao UniversityThe Affiliated Hospital of Qingdao UniversityThe Affiliated Hospital of Qingdao UniversityThe Affiliated Hospital of Qingdao UniversityAbstract Atrial fibrillation is the most common arrhythmia in adults. The interplay between epicardial adipose tissue and atrial fibrillation has garnered significant scientific interest. Recently, the combined approach of radiofrequency ablation and left atrial appendage occlusion has become a widely adopted strategy for managing non-valvular atrial fibrillation patients at high risk of thrombus formation. This study aims to assess the prognostic significance of epicardial adipose tissue volume in patients undergoing radiofrequency ablation in conjunction with left atrial appendage occlusion. This study results indicate that in patients undergoing the one-stop procedure, which comprises catheter radiofrequency ablation and percutaneous left atrial appendage occlusion, epicardial adipose tissue volume is significantly associated with AF recurrence post-strategy. Higher EATV predicts AF recurrence (HR = 1.17, 95%CI1.047-1.192, P = 0.001) and thromboembolism (P = 0.002) following the one-stop procedure. Epicardial adipose tissue volume serves as a significant predictor of atrial fibrillation recurrence following the one-stop procedure (area under the curve 0.648, 95%CI0.571-0.725, P = 0.002, sensitivity 0.88, specificity 0.50).https://doi.org/10.1038/s41598-024-79873-3Atrial fibrillationEpicardial adipose tissueLeft atrial appendage occlusionTranscatheter cardiac radiofrequency ablationThromboembolism |
| spellingShingle | Yuefeng Ju MaoJing Wang Yang Ji Zhihui Wang Wenzhuo Wang Feiyue Liu Siqi Yin Qing Zhao The influence of epicardial adipose tissue on the prognosis of atrial fibrillation patients undergoing radiofrequency ablation combined with left atrial appendage occlusion Scientific Reports Atrial fibrillation Epicardial adipose tissue Left atrial appendage occlusion Transcatheter cardiac radiofrequency ablation Thromboembolism |
| title | The influence of epicardial adipose tissue on the prognosis of atrial fibrillation patients undergoing radiofrequency ablation combined with left atrial appendage occlusion |
| title_full | The influence of epicardial adipose tissue on the prognosis of atrial fibrillation patients undergoing radiofrequency ablation combined with left atrial appendage occlusion |
| title_fullStr | The influence of epicardial adipose tissue on the prognosis of atrial fibrillation patients undergoing radiofrequency ablation combined with left atrial appendage occlusion |
| title_full_unstemmed | The influence of epicardial adipose tissue on the prognosis of atrial fibrillation patients undergoing radiofrequency ablation combined with left atrial appendage occlusion |
| title_short | The influence of epicardial adipose tissue on the prognosis of atrial fibrillation patients undergoing radiofrequency ablation combined with left atrial appendage occlusion |
| title_sort | influence of epicardial adipose tissue on the prognosis of atrial fibrillation patients undergoing radiofrequency ablation combined with left atrial appendage occlusion |
| topic | Atrial fibrillation Epicardial adipose tissue Left atrial appendage occlusion Transcatheter cardiac radiofrequency ablation Thromboembolism |
| url | https://doi.org/10.1038/s41598-024-79873-3 |
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