Photodynamic therapy in a patient with hpv-associated lsil of the cervice (clinical case)

The article describes a clinical example of timely, safe and effective photodynamic therapy (PDT) in a patient diagnosed with human papillomavirus (HPV) CIN I-associated cervical cancer after ineffective vaccination with 4-valent Gardasil vaccine. Clinical case demonstrates the low effectiveness of...

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Main Authors: E. V. Filonenko, N. I. Grigoryevykh, A. D. Kaprin
Format: Article
Language:Russian
Published: Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association" 2022-11-01
Series:Biomedical Photonics
Subjects:
Online Access:https://www.pdt-journal.com/jour/article/view/553
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author E. V. Filonenko
N. I. Grigoryevykh
A. D. Kaprin
author_facet E. V. Filonenko
N. I. Grigoryevykh
A. D. Kaprin
author_sort E. V. Filonenko
collection DOAJ
description The article describes a clinical example of timely, safe and effective photodynamic therapy (PDT) in a patient diagnosed with human papillomavirus (HPV) CIN I-associated cervical cancer after ineffective vaccination with 4-valent Gardasil vaccine. Clinical case demonstrates the low effectiveness of HPV vaccination in patients with established HPV infection. In this patient, the lack of adequate treatment for about 1.5 years led to the development of HPV associated CIN I of the cervix. Center for Laser and Photodynamic Diagnostics and Therapy of Tumors and MRI P.A. Herzen, the patient underwent a course of antiviral PDT with the achievement of complete regression of dysplasia and complete eradication of HPV viruses. The patient tolerated the treatment well, without complications. The period of relapse-free follow-up is 19 months.
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institution Kabale University
issn 2413-9432
language Russian
publishDate 2022-11-01
publisher Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association"
record_format Article
series Biomedical Photonics
spelling doaj-art-642a3669dec9430c872dc43a35d74d272025-08-20T04:00:13ZrusNon-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association"Biomedical Photonics2413-94322022-11-01113404410.24931/2413-9432-2022-11-3-40-44261Photodynamic therapy in a patient with hpv-associated lsil of the cervice (clinical case)E. V. Filonenko0N. I. Grigoryevykh1A. D. Kaprin2P.A. Herzen Moscow Oncology Research Center – branch of FSBI NMRRC of the Ministry of Health of the Russian FederationP.A. Herzen Moscow Oncology Research Center – branch of FSBI NMRRC of the Ministry of Health of the Russian FederationP.A. Herzen Moscow Oncology Research Center – branch of FSBI NMRRC of the Ministry of Health of the Russian FederationThe article describes a clinical example of timely, safe and effective photodynamic therapy (PDT) in a patient diagnosed with human papillomavirus (HPV) CIN I-associated cervical cancer after ineffective vaccination with 4-valent Gardasil vaccine. Clinical case demonstrates the low effectiveness of HPV vaccination in patients with established HPV infection. In this patient, the lack of adequate treatment for about 1.5 years led to the development of HPV associated CIN I of the cervix. Center for Laser and Photodynamic Diagnostics and Therapy of Tumors and MRI P.A. Herzen, the patient underwent a course of antiviral PDT with the achievement of complete regression of dysplasia and complete eradication of HPV viruses. The patient tolerated the treatment well, without complications. The period of relapse-free follow-up is 19 months.https://www.pdt-journal.com/jour/article/view/553cervical dysplasiacinphotodynamic therapyphotosensitizerhpv infection
spellingShingle E. V. Filonenko
N. I. Grigoryevykh
A. D. Kaprin
Photodynamic therapy in a patient with hpv-associated lsil of the cervice (clinical case)
Biomedical Photonics
cervical dysplasia
cin
photodynamic therapy
photosensitizer
hpv infection
title Photodynamic therapy in a patient with hpv-associated lsil of the cervice (clinical case)
title_full Photodynamic therapy in a patient with hpv-associated lsil of the cervice (clinical case)
title_fullStr Photodynamic therapy in a patient with hpv-associated lsil of the cervice (clinical case)
title_full_unstemmed Photodynamic therapy in a patient with hpv-associated lsil of the cervice (clinical case)
title_short Photodynamic therapy in a patient with hpv-associated lsil of the cervice (clinical case)
title_sort photodynamic therapy in a patient with hpv associated lsil of the cervice clinical case
topic cervical dysplasia
cin
photodynamic therapy
photosensitizer
hpv infection
url https://www.pdt-journal.com/jour/article/view/553
work_keys_str_mv AT evfilonenko photodynamictherapyinapatientwithhpvassociatedlsilofthecerviceclinicalcase
AT nigrigoryevykh photodynamictherapyinapatientwithhpvassociatedlsilofthecerviceclinicalcase
AT adkaprin photodynamictherapyinapatientwithhpvassociatedlsilofthecerviceclinicalcase