Betrixaban is a broad anti-virus inhibitor by activating innate immunity

Betrixaban is a broad anti-virus inhibitor by activating innate immunity

The innate immune system serves as the first line of defense against viral infections. Type I interferon (IFN-I) signaling, in particular, plays a crucial role in mediating antiviral immunity. Here, we identify Betrixaban (BT), a novel small-molecule compound that activates innate immune responses,...

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Bibliographic Details
Main Authors: Shiyu Hu, Yang Zhao, Xingyu Chen, Haocheng Wang, Wenjun Hu, Rong Huang, Jian Yang, Chenxi Niu, Xuefei Guo, Fuping You
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
broad-spectrum antiviral
Betrixaban
FXa
innate immunity
VSV
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1603530/full
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