Novel research model for in vitro immunotherapy: co-culturing tumor organoids with peripheral blood mononuclear cells
Abstract Tumor organoids have emerged as powerful tools for in vitro cancer research due to their ability to retain the structural and genetic characteristics of tumors. Nevertheless, the absence of a complete tumor microenvironment (TME) limits the broader application of organoid models in immunolo...
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Main Authors: | Peng Li, Minli Huang, Yifan Ma, Yongbin Zhang, Changhong Shi |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-12-01
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Series: | Cancer Cell International |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12935-024-03628-3 |
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