Axodendritic targeting of TAU and MAP2 and microtubule polarization in iPSC-derived versus SH-SY5Y-derived human neurons
Cell polarity is crucial in neurons, characterized by distinct axonal and dendritic structures. Neurons generally have one long axon and multiple shorter dendrites, marked by specific microtubule (MT)-associated proteins, e.g., MAP2 for dendrites and TAU for axons, while the scaffolding proteins Ank...
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Main Authors: | Breuer Helen, Bell-Simons Michael, Zempel Hans |
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Format: | Article |
Language: | English |
Published: |
De Gruyter
2024-12-01
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Series: | Open Life Sciences |
Subjects: | |
Online Access: | https://doi.org/10.1515/biol-2022-1010 |
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