One Health at Risk: Plasmid-Mediated Spread of <i>mcr-1</i> Across Clinical, Agricultural, and Environmental Ecosystems

One Health at Risk: Plasmid-Mediated Spread of <i>mcr-1</i> Across Clinical, Agricultural, and Environmental Ecosystems

The global dissemination of plasmid-mediated <i>mcr</i> genes, which confer resistance to the last-resort antibiotic colistin, represents a critical public health challenge driven by the interplay of clinical, agricultural, and environmental factors. This review examines the genetic and...

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Bibliographic Details
Main Authors: Abdelaziz Touati, Nasir Adam Ibrahim, Assia Mairi, Hassina Kirat, Nosiba S. Basher, Takfarinas Idres
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Antibiotics
Subjects:
plasmid-mediated resistance
<i>mcr-1</i> gene
colistin resistance
IncI2 plasmids
IncHI2 plasmids
IncX4 plasmids
Online Access:https://www.mdpi.com/2079-6382/14/5/506
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