A Lassa virus live attenuated vaccine candidate that is safe and efficacious in guinea pigs

A Lassa virus live attenuated vaccine candidate that is safe and efficacious in guinea pigs

Abstract Lassa virus (LASV) is a rodent-borne mammarenavirus that causes tens to hundreds of thousands of human infections annually in Western Africa. Approximately 20% of these infections progress to Lassa fever (LF), an acute disease with case–fatality rates from ≈20–70%. Currently, there are no a...

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Main Authors: Brian D. Carey, Shuiqing Yu, Jillian Geiger, Chengjin Ye, Louis M. Huzella, Rebecca J. Reeder, Monika Mehta, Shawn Hirsch, Rebecca Bernbaum, Beatrice Cubitt, Bapi Pahar, Scott M. Anthony, Anthony Marketon, John G. Bernbaum, Julie P. Tran, Ian Crozier, Luis Martínez-Sobrido, Gabriella Worwa, Juan Carlos de la Torre, Jens H. Kuhn
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-024-01012-w
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https://doi.org/10.1038/s41541-024-01012-w

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