GLUCOSE METABOLISM AND INSULIN RESPONSE TO ORAL GLUCOSE TOLERANCE TEST (OGTT) IN PREPUBERTAL PATIENTS WITH TRANSFUSION DEPENDENT Β-THALASSEMIA (TDT): A LONG-TERM RETROSPECTIVE ANALYSIS

GLUCOSE METABOLISM AND INSULIN RESPONSE TO ORAL GLUCOSE TOLERANCE TEST (OGTT) IN PREPUBERTAL PATIENTS WITH TRANSFUSION DEPENDENT Β-THALASSEMIA (TDT): A LONG-TERM RETROSPECTIVE ANALYSIS

Background: Glucose dysregulation (GD), including prediabetes and diabetes mellitus (DM), is a common complication of transfusion dependent β-thalassemia (TDT) patients. The prevalence increases with age and magnitude of iron overload, affecting a significant proportion of patients. The development...

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Bibliographic Details
Main Authors: Vincenzo De Sanctis, Ashraf Soliman, Ploutarchos Tzoulis, Shahina Daar, Salvatore Di Maio, Bernadette Fiscina, Christos Kattamis
Format: Article
Language:English
Published: PAGEPress Publications 2021-08-01
Series:Mediterranean Journal of Hematology and Infectious Diseases
Subjects:
Thalassemia, iron overload, oral glucose tolerance test, type 2 diabetes mellitus, insulin secretion and sensitivity indices, long-term follow-up.
Online Access:https://www.mjhid.org/index.php/mjhid/article/view/4623
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