Acute Chikungunya Infection Induces Vascular Dysfunction by Directly Disrupting Redox Signaling in Endothelial Cells

Acute Chikungunya Infection Induces Vascular Dysfunction by Directly Disrupting Redox Signaling in Endothelial Cells

Chikungunya virus (CHIKV) infection is characterized by febrile illness, severe joint pain, myalgia, and cardiovascular complications. Given that CHIKV stimulates reactive oxygen species (ROS) and pro- and anti-inflammatory cytokines, events that disrupt vascular homeostasis, we hypothesized that CH...

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Bibliographic Details
Main Authors: José Teles de Oliveira-Neto, Juliano de P. Souza, Daniel Rodrigues, Mirele R. Machado, Juliano V. Alves, Paula R. Barros, Alecsander F. Bressan, Josiane F. Silva, Tiago J. Costa, Rafael M. Costa, Daniella Bonaventura, Eurico de Arruda-Neto, Rita C. Tostes, Emiliana P. Abrão
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Cells
Subjects:
Chikungunya
reactive oxygen species
nitric oxide synthase
vascular dysfunction
Online Access:https://www.mdpi.com/2073-4409/13/21/1770
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